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Increased expression and altered location of annexin IV in renal clear cell carcinoma: a possible role in tumour dissemination.
The proteome of renal cell carcinoma and non-neoplastic kidney tissue was analysed from 12 patients by two-dimensional polyacrylamide gel electrophoresis to search for differentially expressedExpand
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Investigation of Schwann cells at neoplastic cell sites before the onset of cancer invasion.
BACKGROUND In neural invasion (NI), cancer cells are classically assumed to actively invade nerves and to cause local recurrence and pain. However, the opposite possibility, that nerves may reachExpand
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Prohibitin identified by proteomic analysis of prostate biopsies distinguishes hyperplasia and cancer.
Prostate cancer (PCA) is the most common type of cancer found in men of western countries and is the leading cancer death next to lung cancer and colorectal cancer. Prostate-specific antigen (PSA)Expand
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Altered expression of tumor protein D52 regulates apoptosis and migration of prostate cancer cells
Tumor protein D52 (TPD52) is a protein found to be overexpressed in prostate and breast cancer due to gene amplification. However, its physiological function remains under investigation. In theExpand
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Präzision der navigationsgestützten Chirurgie an der Brust- und Lendenwirbelsäule
ZusammenfassungZiel der vorliegenden Studien ist die Evaluierung der klinischen und im Labor erreichbaren Präzision der CT- und C-Arm-basierten navigierten Zielweisung am Pedikel der Brust- (BWS) undExpand
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Association Analysis of Genetic Variants in the Myosin IXB Gene in Acute Pancreatitis
Introduction Impairment of the mucosal barrier plays an important role in the pathophysiology of acute pancreatitis. The myosin IXB (MYO9B) gene and the two tight-junction adaptor genes, PARD3 andExpand
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Early pancreatic cancer lesions suppress pain through CXCL12-mediated chemoattraction of Schwann cells
Significance Pancreatic ductal adenocarcinoma cancer (PDAC) cells have an exceptional propensity to invade nerves via pronounced crosstalk between nerves and cancer cells, but the mechanisms of thisExpand
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Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer
Objective Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies and is projected to be the second leading cause of cancer-related death by 2030. Despite extensiveExpand
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Genetically induced vs. classical animal models of chronic pancreatitis: a critical comparison
Chronic pancreatitis (CP) is an utmost complex disease that is pathogenetically linked to pancreas‐ intrinsic (e.g., duct obstruction), environmental‐toxic (e.g., alcohol, smoking), and geneticExpand
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The pharmacokinetic‐pharmacodynamic (Digit Symbol Substitution Test) relationship of flumazenil in a midazolam steady‐state model in healthy volunteers
To characterize the plasma concentration–effect relationship of flumazenil in the presence of a predefined midazolam level, a double‐blind, placebo‐controlled, randomized two‐way crossover study wasExpand
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