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The pregnancy-specific glycoprotein (PSG) gene cluster on human chromosome 19: fine structure of the 11 PSG genes and identification of 6 new genes forming a third subgroup within the…
- S. Teglund, A. Olsén, W. Khan, L. Frängsmyr, S. Hammarström
- Biology, Medicine
- Genomics
- 1 October 1994
The human pregnancy-specific glycoprotein (PSG) genes belong to the carcinoembryonic antigen (CEA) family, which in turn is a member of the immunoglobulin superfamily. We have analyzed a 700-kb… Expand
Characterization of cDNA encoding novel pregnancy-specific glycoprotein variants.
- S. Teglund, G. Q. Zhou, S. Hammarström
- Biology, Medicine
- Biochemical and biophysical research…
- 15 June 1995
The human pregnancy-specific glycoprotein (PSG) family consists of eleven closely related molecules mainly synthesized by placental syncytiotrophoblasts and whose function(s) are unknown. They belong… Expand
Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region.
- A. Olsen, S. Teglund, +5 authors S. Hammarström
- Biology, Medicine
- Genomics
- 1 October 1994
The pregnancy-specific glycoprotein (PSG) gene family consists of 11 closely related genes that form a subgroup of the carcinoembryonic antigen (CEA) gene family on 19q13.2. Using a high-resolution… Expand
The pregnancy-specific glycoprotein family of the immunoglobulin superfamily: identification of new members and estimation of family size.
- W. Khan, S. Teglund, K. Bremer, S. Hammarström
- Biology, Medicine
- Genomics
- 1 April 1992
The members of the carcinoembryonic antigen (CEA)/pregnancy-specific glycoprotein (PSG) gene family have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region.… Expand
Identification of three new genes and estimation of the size of the carcinoembryonic antigen family.
- W. Khan, L. Frängsmyr, S. Teglund, A. Israelsson, K. Bremer, S. Hammarström
- Biology, Medicine
- Genomics
- 1 October 1992
Using carcinoembryonic antigen (CEA) subgroup-specific degenerate PCR primers, we have identified three new CEA gene family member L/N exons (CGM9, CGM10, and CGM11) and all previously reported L/N… Expand
Evolution of the Carcinoembryonic Antigen Family
- L. Frängsmyr, A. Israelsson, S. Teglund, T. Matsunaga, S. Hammarström
- Biology, Medicine
- Tumor Biology
- 18 February 2000
Earlier studies have demonstrated that the genes of the human carcinoembryonic antigen (CEA) family can be divided into three subgroups, the CEA subgroup (n = 12), the pregnancy-specific glycoprotein… Expand
Intra-and inter-individual heterogeneity in exon 2 of the MDR1 gene in primary breast carcinoma and healthy individuals.
- Y. Aalto, S. Teglund, U. Andersson, G. Blanco, S. Hammarstrom, R. Henriksson
- Biology, Medicine
- International journal of oncology
- 1 October 1997
Increased expression of P-glycoprotein, encoded by the MDR1 gene, is considered to be responsible for chemotherapy failure in a number of human cancers. Although it is clear that mutations in the… Expand