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A visual motion detection circuit suggested by Drosophila connectomics
Animal behaviour arises from computations in neuronal circuits, but our understanding of these computations has been frustrated by the lack of detailed synaptic connection maps, or connectomes. ForExpand
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The Neural Substrate of Spectral Preference in Drosophila
Drosophila vision is mediated by inputs from three types of photoreceptor neurons; R1-R6 mediate achromatic motion detection, while R7 and R8 constitute two chromatic channels. Neural circuits forExpand
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A connectome of a learning and memory center in the adult Drosophila brain
Understanding memory formation, storage and retrieval requires knowledge of the underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of associative learning. WeExpand
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The comprehensive connectome of a neural substrate for ‘ON’ motion detection in Drosophila
We reconstructed a comprehensive connectome of the circuits of Drosophila‘s motion-sensing T4 cells using a novel EM technique. Expand
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Synaptic circuits of the Drosophila optic lobe: The input terminals to the medulla
Understanding the visual pathways of the fly's compound eye has been blocked for decades at the second optic neuropil, the medulla, a two‐part relay comprising 10 strata (M1–M10), and the largestExpand
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Synaptic circuits and their variations within different columns in the visual system of Drosophila
Significance Circuit diagrams of brains are generally reported only as absolute or consensus networks; these diagrams fail to identify the accuracy of connections, however, for which multipleExpand
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Cholinergic Circuits Integrate Neighboring Visual Signals in a Drosophila Motion Detection Pathway
Detecting motion is a feature of all advanced visual systems [1], nowhere more so than in flying animals, like insects [2, 3]. In flies, an influential autocorrelation model for motion detection, theExpand
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Ig Superfamily Ligand and Receptor Pairs Expressed in Synaptic Partners in Drosophila
Information processing relies on precise patterns of synapses between neurons. The cellular recognition mechanisms regulating this specificity are poorly understood. In the medulla of the DrosophilaExpand
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Wiring Economy and Volume Exclusion Determine Neuronal Placement in the Drosophila Brain
Wiring economy has successfully explained the individual placement of neurons in simple nervous systems like that of Caenorhabditis elegans [1–3] and the locations of coarser structures like corticalExpand
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A Connectome of the Adult Drosophila Central Brain
The neural circuits responsible for behavior remain largely unknown. Previous efforts have reconstructed the complete circuits of small animals, with hundreds of neurons, and selected circuits forExpand
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