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Dermatologist-level classification of skin cancer with deep neural networks
We train a CNN using a dataset of 129,450 clinical images—two orders of magnitude larger than previous datasets—consisting of 2,032 different diseases. Expand
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
This corrects the article DOI: 10.1038/nature09161
Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients
We identified circulating CD8+ T-cell populations specific for the tumor-associated antigens (TAAs) MART-1 (27-35) or tyrosinase (368-376) in six of eleven patients with metastatic melanoma usingExpand
Increasing burden of melanoma in the United States.
It is controversial whether worldwide increases in melanoma incidence represent a true epidemic. Dramatic increases in incidence in the setting of relatively stable mortality trends have also beenExpand
Human Melanoma Initiating Cells Express Neural Crest Nerve Growth Factor Receptor CD271
The question of whether tumorigenic cancer stem cells exist in human melanomas has arisen in the last few years. Here we show that in melanomas, tumour stem cells (MTSCs, for melanoma tumour stemExpand
Impaired interferon signaling is a common immune defect in human cancer
Immune dysfunction develops in patients with many cancer types and may contribute to tumor progression and failure of immunotherapy. Mechanisms underlying cancer-associated immune dysfunction are notExpand
Melanoma, Version 2.2016, NCCN Clinical Practice Guidelines in Oncology.
This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Melanoma focuses on adjuvant therapy and treatment of in-transit disease, because substantial changes wereExpand
Screening, early detection, and trends for melanoma: current status (2000-2006) and future directions.
UNLABELLED In the past 5 years, there have been notable strides toward the earlier recognition and discovery of melanoma, including new technologies to complement and augment the clinical examinationExpand
A Prospective Clinical Trial Combining Radiation Therapy With Systemic Immunotherapy in Metastatic Melanoma.
PURPOSE Local radiation therapy (RT) combined with systemic anti-cytotoxic T-lymphocyte-associated protein-4 immunotherapy may enhance induction of systemic antimelanoma immune responses. The primaryExpand
Increasing incidence of lentigo maligna melanoma subtypes: northern California and national trends 1990-2000.
Worldwide, lentigo maligna melanoma (LMM) comprises 4%-15% of cutaneous melanoma and occurs less commonly than superficial spreading or nodular subtypes. We assessed the incidence of melanomaExpand