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Rapid induction of seven proteins in human lymphocytes by interferon; correlation to natural killer cell activity.
The early effects of interferon (IFN) on the synthesis of protein in human nylon wool-nonadherent lymphocytes have been stimulated by use of two-dimensional electrophoresis. IFN-alpha or -beta asExpand
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The augmentation of human natural killer cell activity by interferon-gamma is not associated with the induction of the interferon-alpha-inducible proteins.
Treatment of partly purified large granular lymphocytes (LGL) with either IFN-alpha or IFN-gamma for 2 hr augmented their NK cell activity. This augmentation was completely inhibited by the additionExpand
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Growth-state independent induction of specific proteins in Swiss 3T3 cells by interferon.
The early effects of interferon (IFN) on the pattern of protein synthesis in Swiss 3T3 mouse fibroblasts were investigated by two-dimensional gel electrophoresis of 35S-methionine labeled cellExpand
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Dopamine actions in vitro on enzyme and electrolyte secretion from normal and sympathectomized rat parotid glands.
1. Adult rats were denervated unilaterally by removal of the left superior cervical ganglion or chemically denervated with 6‐hydroxydopamine or reserpine. Two weeks later the parotid glands were usedExpand
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Fractionated irradiation and early changes in salivary glands. Different effects on potassium efflux, exocytotic amylase release and gland morphology.
Irradiation is a potent treatment modality of head and neck cancer. However, the irradiation is usually associated with an influence on salivary glands with ensuing dryness and discomfort for theExpand
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Developmental influences of the sympathetic nervous system on rat parotid gland
In an attempt to evaluate the effect of the sympathetic nervous system on the postnatal maturation of the parotid gland, rats were either sympathetically denervated on one side by avulsion of theExpand
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Fractionated irradiation and late changes in rat parotid gland: effects on the number of acinar cells, potassium efflux, and amylase secretion.
Irradiation of head- and neck cancer commonly results in oral dryness and discomfort for the patients due to salivary gland damage. The exact mechanisms behind the inherent radiosensitivity ofExpand
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Interferon‐specific effects on protein synthesis in P3HR‐1 cells.
The effect of interferon (IFN) on protein synthesis was studied in the Burkitt's lymphoma cell line P3HR‐1 by [35S]methionine labelling of the cells, followed by two‐dimensional gel electrophoresisExpand
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Effects of chronic stimulation of salivary gland beta-adrenoceptors on saliva composition and caries development in the rat.
The effects of long-term beta-adrenoceptor stimulation or inhibition on parotid and submandibular glands, saliva secretion, and caries development were studied. Groups of rats were treated dailyExpand
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Inhomogeneities in glycoprotein cytochemistry of secretory granules in rat-parotid acinar cells after selective beta 1-adrenoceptor stimulation.
The distribution of periodate-positive glycoproteins was studied in parotid acinar cells of the rat after stimulation with the specific beta 1-adrenoceptor agonist prenalterol. After two weeks ofExpand
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