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eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences
TLDR
We present a public resource that provides Orthologous Groups (OGs) of proteins at different taxonomic levels, each with integrated and summarized functional annotations. Expand
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Structure and function of the global ocean microbiome
Microbes are dominant drivers of biogeochemical processes, yet drawing a global picture of functional diversity, microbial community structure, and their ecological determinants remains a grandExpand
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An integrated catalog of reference genes in the human gut microbiome
Many analyses of the human gut microbiome depend on a catalog of reference genes. Existing catalogs for the human gut microbiome are based on samples from single cohorts or on reference genomes orExpand
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Richness of human gut microbiome correlates with metabolic markers
We are facing a global metabolic health crisis provoked by an obesity epidemic. Here we report the human gut microbial composition in a population sample of 123 non-obese and 169 obese DanishExpand
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Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
TLDR
We show, using 784 available human gut metagenomes, howantidiabetic medication confounds these results, and analyse in detail the effects of the most widely used antidiabetic drug metformin. Expand
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Potential of fecal microbiota for early-stage detection of colorectal cancer
Several bacterial species have been implicated in the development of colorectal carcinoma (CRC), but CRC‐associated changes of fecal microbiota and their potential for cancer screening remain to beExpand
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Eukaryotic plankton diversity in the sunlit ocean
Marine plankton support global biological and geochemical processes. Surveys of their biodiversity have hitherto been geographically restricted and have not accounted for the full range of planktonExpand
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Threatened Corals Provide Underexplored Microbial Habitats
Contemporary in-depth sequencing of environmental samples has provided novel insights into microbial community structures, revealing that their diversity had been previously underestimated.Expand
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Bacterial diversity and White Plague Disease-associated community changes in the Caribbean coral Montastraea faveolata
Increasing evidence confirms the crucial role bacteria and archaea play within the coral holobiont, that is, the coral host and its associated microbial community. The bacterial component constitutesExpand
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Symbiodinium Transcriptomes: Genome Insights into the Dinoflagellate Symbionts of Reef-Building Corals
Dinoflagellates are unicellular algae that are ubiquitously abundant in aquatic environments. Species of the genus Symbiodinium form symbiotic relationships with reef-building corals and other marineExpand
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