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Plasma levels of pentosidine in diabetic patients: an advanced glycation end product.
TLDR
It is demonstrated that plasma pentosidine level was significantly influenced by the quality of glycemic control and renal function, and might be taken as a biomarker of diabetic cardiovascular risk. Expand
A PROSPECTIVE STUDY OF HUMAN HERPESVIRUS‐6 INFECTION IN RENAL TRANSPLANTATION
TLDR
Results indicate that the virus is activated in many cases in the early posttransplant period and that HHV-6 establishes in vivo latency in the kidney tissue. Expand
Accumulation of Bisphenol A in Hemodialysis Patients
TLDR
Among renal disease patients who had not undergone hemodialysis, the serum BPA concentration increased as the renal function deteriorated, showing a significant negative association with BPA. Expand
Serum under-galactosylated IgA1 is increased in Japanese patients with IgA nephropathy.
TLDR
HAA-IgA binding is significantly increased in Japanese IgAN patients and the O-glycan structure of IgA1 hinge glycopeptides was shifted to smaller molecular weights in high HAA- IgA-binding IgAN Patients. Expand
Clearance of pentosidine, an advanced glycation end product, by different modalities of renal replacement therapy.
TLDR
The findings demonstrate that both HD and CAPD remove Pfree; the peritoneal clearance of Palb, might contribute to the lower level of plasma pentosidine in CAPD than in HD patients; and renal transplantation is the best therapeutic modality to normalize both Palb and Pfree levels. Expand
Reactive carbonyl compounds related uremic toxicity ("carbonyl stress").
TLDR
This article describes the causal role of various RCOs and AGEs/ALEs accumulating in uremia, the clinical consequences of carbonyl stress in u Remia, and the therapeutic perspectives, and proposes carbonyL stress as a new uremic toxicity. Expand
Immediate therapeutic efficacy of low-density lipoprotein apheresis for drug-resistant nephrotic syndrome: evidence from the short-term results from the POLARIS Study
TLDR
An analysis of patients registered in the POLARIS study indicated that LDL-A has short-term efficacy for drug-resistant NS, and rapid relief of dyslipidemia by LDL- A may provide early remission in about half of the NS patients who are resistant to conventional medication. Expand
In a type 2 diabetic nephropathy rat model, the improvement of obesity by a low calorie diet reduces oxidative/carbonyl stress and prevents diabetic nephropathy.
TLDR
A direct role of obesity is suggested in the generation of a localized oxidative stress and AGE formation, directly responsible for diabetic nephropathy. Expand
The HLA-DRB1*1501 allele is prevalent among Japanese patients with anti-glomerular basement membrane antibody-mediated disease.
TLDR
It is demonstrated that Japanese patients with anti-GBM antibody-mediated disease are very likely to carry the HLA-DRB1(*)1501 but not the HBA(*)1502 allele. Expand
Induction of irreversible glomerulosclerosis in the rat by repeated injections of a monoclonal anti-Thy-1.1 antibody.
TLDR
The present experiment demonstrated that an irreversible glomerulosclerosis could be induced in the rat through repeated intravenous administrations of OX-7 (a monoclonal anti-Thy-1.1 antibody), and could serve as a potential for further investigation of the mechanisms involved in the development of chronicglomerulonephritis. Expand
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