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Citrus aurantium (bitter orange) extract: Safety assessment by acute and 14‐day oral toxicity studies in rats and the Ames Test for mutagenicity
ABSTRACT The primary active constituent in bitter orange extract (BOE) is p‐synephrine. This study assessed the safety of a BOE standardized to 50% p‐synephrine following short‐term exposure to ratsExpand
Altered metabolism of androstenedione by hepatic microsomes from streptozotocin-diabetic male rats.
The total metabolism of androstenedione by hepatic microsomes from streptozotocin-diabetic male rats was decreased from corresponding control values. Microsomal androstenedione 7alpha-hydroxylaseExpand
Sapogenins of Yucca glauca tissue cultures.
Identification of cytidine diphosphodiesters in erythrocytes from a patient with pyrimidine nucleotidase deficiency.
Pyrimidine 5'-nucleotidase deficient (PND) erythrocytes contain elevated levels of pyrimidine nucleotides and relatively normal purine nucleotide levels. The composition of this nucleotide pool hasExpand
Lead-induced accumulation of erythrocyte pyrimidine nucleotides in the rabbit.
Abstract Rabbits fed lead acetate, 30 mg/kg/day, had a rapid decrease in erythrocyte pyrimidine 5′ nucleotidase (P5N; EC 3.1.3.5) to 38% of control activity by 30 days at which time mean blood leadExpand
Erythrocyte arginase, pyrimidine 5'-nucleotidase (P5N), and deoxypyrimidine 5'-nucleotidase (dP5N) as indices of lead exposure.
The activities of three erythrocyte (rbc) enzymes, arginase, pyrimidine 5'-nucleotidase (P5N), and deoxypyrimidine 5'-nucleotidase (dP5N), were compared in 16 lead workers and 14 age matched controlsExpand
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