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Meticillin-resistant Staphylococcus aureus (MRSA): global epidemiology and harmonisation of typing methods.
The group consensus was to recommend spa and staphylococcal cassette chromosome mec (SCCmec) typing as the preferred methods for MRSA, which are informative in defining particular strain characteristics and utilise standardised nomenclatures, making them applicable globally. Expand
Tackling antibiotic resistance: the environmental framework
The main knowledge gaps, the future research needs and the policy and management options that should be prioritized to tackle antibiotic resistance in the environment are discussed. Expand
Macrolide Efflux Genes mef(A) and mef(E) Are Carried by Different Genetic Elements in Streptococcus pneumoniae
It is suggested that the distinction between the two genes be maintained in Streptococcus pneumoniae isolates, because of the important different characteristics of the strains carrying mef(A) or me f(E). Expand
Enterobacter cloacae complex: clinical impact and emerging antibiotic resistance.
The biochemical and molecular studies on E. cloacae have shown genomic heterogeneity, comprising six species, which are capable of overproducing AmpC β-lactamases by derepression of a chromosomal gene or by the acquisition of a transferable ampC gene on plasmids conferring the antibiotic resistance. Expand
Antibiotic resistance in Pseudomonas aeruginosa: an Italian survey.
The University of Catania tested the antibiotic susceptibility of 1005 consecutive clinically significant P. aeruginosa isolates collected from March to June 1995, finding that about half of the isolates were not susceptible to at least one of the antibiotics tested. Expand
Presence of the ica operon in clinical isolates of Staphylococcus epidermidis and its role in biofilm production.
The results showed that icaRADBC was present in 45% of the isolates included in the study, and that such isolates were significantly more resistant to the main antibiotics tested than were ica-negative isolates, and there was evidence to suggest a correlation when at least two genes (icaAD) were co-transcribed. Expand
CTX-M-Type Extended-Spectrum β-Lactamases in Italy: Molecular Epidemiology of an Emerging Countrywide Problem
The present results indicate that CTX-M-producing strains are now widespread across the Italian territory and underscore the emerging role of these ESBL determinants in the European setting. Expand
Burkholderia cepacia Complex Infection in Italian Patients with Cystic Fibrosis: Prevalence, Epidemiology, and Genomovar Status
Of all the strains of B. cepacia encountered in the Italian CF population, the genomovar III, recA group III-A strains were the most prevalent and transmissible, however, patient-to-patient spread was also observed with several other genomOVars, including strains of novel taxonomic status within the B. Cepacia complex. Expand
Characterization of a Genetic Element Carrying the Macrolide Efflux Gene mef(A) in Streptococcus pneumoniae
ABSTRACT The mef(A) gene from a clinical isolate ofStreptococcus pneumoniae exhibiting the M-type resistance to macrolides was found to be part of the 7,244-bp chromosomal element Tn1207.1, whichExpand
Hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) in Italy
The alternation of MRSA clones that occurred in hospitals from 1990 to 2007 and the increase of the glycopeptide MIC levels, reflecting a worldwide trend are described. Expand