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Transplantation of lungs from a non-heart-beating donor
BACKGROUND In animals, we have previously done successful lung transplantations using organs from non-heart-beating donors. We have also developed an ex-vivo system of assessing the function of such… Expand
Transplantation of lungs from non-heart-beating donors after functional assessment ex vivo.
- S. Steen, Q. Liao, P. Wierup, R. Bolys, Leif Pierre, T. Sjöberg
- The Annals of thoracic surgery
- 1 July 2003
BACKGROUND If lungs from patients dying of heart attacks are to serve as donor organs in a safe way, their function should be properly assessed before transplantation. The aim of this study was to… Expand
Evaluation of LUCAS, a new device for automatic mechanical compression and active decompression resuscitation.
LUCAS is a new gas-driven CPR device providing automatic chest compression and active decompression. In an artificial thorax model, superior pressure and flow were obtained with LUCAS compared with… Expand
Clinical transplantation of initially rejected donor lungs after reconditioning ex vivo.
BACKGROUND A major problem in clinical lung transplantation is the shortage of donor lungs. Only about 20% of donor lungs are accepted for transplantation. A method to evaluate and recondition lungs… Expand
The critical importance of minimal delay between chest compressions and subsequent defibrillation: a haemodynamic explanation.
Outcome after prehospital defibrillation remains dire. The aim of the present study was to elucidate the pathophysiology of cardiac arrest and to suggest ways to improve outcome. Ventricular… Expand
First human transplantation of a nonacceptable donor lung after reconditioning ex vivo.
PURPOSE This article describes an ex vivo method to recondition and transplant rejected donor lungs. DESCRIPTION A 19-year-old man was brain dead after a traffic accident. A roentgenogram showed… Expand
Combined use of hypothermia and buffering in the treatment of critical respiratory failure
A 20‐year‐old male, recovering from post‐traumatic ARDS, subsequently developed pneumonia with extreme hypercapnia (Paco2 max 19.4 kPa) and hypoxemia (Pao2 min 5.1 kPa), in spite of maximal… Expand
Manual versus mechanical cardiopulmonary resuscitation. An experimental study in pigs
- Q. Liao, T. Sjöberg, A. Paskevicius, B. Wohlfart, S. Steen
- BMC cardiovascular disorders
- 28 October 2010
BackgroundOptimal manual closed chest compressions are difficult to give. A mechanical compression/decompression device, named LUCAS, is programmed to give compression according to the latest… Expand
Mechanical removal of dendritic cell-generating non-classical monocytes via ex vivo lung perfusion.
- J. Stone, Hannah Sevenoaks, T. Sjöberg, S. Steen, N. Yonan, J. Fildes
- The Journal of heart and lung transplantation…
- 1 August 2014
BACKGROUND Ex vivo lung perfusion (EVLP) is a novel procedure designed to rapidly assess and recondition unusable donor lungs for transplantation (LTx). EVLP may reduce graft immunogenicity and… Expand
Ex vivo evaluation of nonacceptable donor lungs.
BACKGROUND Only a minority of the potential candidates for lung donation are considered suitable, using current evaluation methods. A new method for ex vivo evaluation, with the potential for… Expand