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Transplantation of lungs from a non-heart-beating donor
BACKGROUND In animals, we have previously done successful lung transplantations using organs from non-heart-beating donors. We have also developed an ex-vivo system of assessing the function of suchExpand
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Transplantation of lungs from non-heart-beating donors after functional assessment ex vivo.
BACKGROUND If lungs from patients dying of heart attacks are to serve as donor organs in a safe way, their function should be properly assessed before transplantation. The aim of this study was toExpand
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Evaluation of LUCAS, a new device for automatic mechanical compression and active decompression resuscitation.
LUCAS is a new gas-driven CPR device providing automatic chest compression and active decompression. In an artificial thorax model, superior pressure and flow were obtained with LUCAS compared withExpand
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Clinical transplantation of initially rejected donor lungs after reconditioning ex vivo.
BACKGROUND A major problem in clinical lung transplantation is the shortage of donor lungs. Only about 20% of donor lungs are accepted for transplantation. A method to evaluate and recondition lungsExpand
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The critical importance of minimal delay between chest compressions and subsequent defibrillation: a haemodynamic explanation.
Outcome after prehospital defibrillation remains dire. The aim of the present study was to elucidate the pathophysiology of cardiac arrest and to suggest ways to improve outcome. VentricularExpand
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First human transplantation of a nonacceptable donor lung after reconditioning ex vivo.
PURPOSE This article describes an ex vivo method to recondition and transplant rejected donor lungs. DESCRIPTION A 19-year-old man was brain dead after a traffic accident. A roentgenogram showedExpand
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Combined use of hypothermia and buffering in the treatment of critical respiratory failure
A 20‐year‐old male, recovering from post‐traumatic ARDS, subsequently developed pneumonia with extreme hypercapnia (Paco2 max 19.4 kPa) and hypoxemia (Pao2 min 5.1 kPa), in spite of maximalExpand
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Manual versus mechanical cardiopulmonary resuscitation. An experimental study in pigs
BackgroundOptimal manual closed chest compressions are difficult to give. A mechanical compression/decompression device, named LUCAS, is programmed to give compression according to the latestExpand
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Mechanical removal of dendritic cell-generating non-classical monocytes via ex vivo lung perfusion.
BACKGROUND Ex vivo lung perfusion (EVLP) is a novel procedure designed to rapidly assess and recondition unusable donor lungs for transplantation (LTx). EVLP may reduce graft immunogenicity andExpand
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Ex vivo evaluation of nonacceptable donor lungs.
BACKGROUND Only a minority of the potential candidates for lung donation are considered suitable, using current evaluation methods. A new method for ex vivo evaluation, with the potential forExpand
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