• Publications
  • Influence
A trial of imaging selection and endovascular treatment for ischemic stroke.
TLDR
A favorable penumbral pattern on neuroimaging did not identify patients who would differentially benefit from endovascular therapy for acute ischemic stroke, nor was embolectomy shown to be superior to standard care.
Safety and Efficacy of Mechanical Embolectomy in Acute Ischemic Stroke: Results of the MERCI Trial
TLDR
A novel endovascular embolectomy device can significantly restore vascular patency during acute ischemic stroke within 8 hours of stroke symptom onset and provides an alternative intervention for patients who are otherwise ineligible for thrombolytics.
Mechanical Thrombectomy for Acute Ischemic Stroke: Final Results of the Multi MERCI Trial
TLDR
Higher rates of recanalization were associated with a newer generation thrombectomy device compared with first-generation devices, but these differences did not achieve statistical significance.
Acute seizures after intracerebral hemorrhage
TLDR
Seizures occur commonly after ICH and may be nonconvulsive and independently associated with increased midline shift after intraparenchymal hemorrhage.
MERCI 1: A Phase 1 Study of Mechanical Embolus Removal in Cerebral Ischemia
TLDR
This phase 1 study shows that cerebral embolectomy with the Merci Retriever was safe and that successful recanalization could benefit a significant number of patients, even when performed in an extended 8-hour time window.
Diffusion MRI in patients with transient ischemic attacks.
TLDR
In nearly half of clinically defined TIA patients, the diffusion MRI changes may be fully reversible, while in the remainder the diffusionMRI findings herald the development of a parenchymal infarct despite transient clinical symptoms.
Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging
TLDR
Serial diffusion and perfusion imaging studies were acquired in patients experiencing acute hemispheric cerebral ischemia treated with intra‐arterial thrombolytic therapy within 6 hours of symptom onset, providing an early marker of acute cerebral ischemic injury.
Combined intravenous and intra-arterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial.
TLDR
This pilot study demonstrates combined IV/IA treatment for stroke within 3 hours of onset of symptoms is feasible and provides better recanalization, although it was not associated with improved clinical outcomes.
CT and MRI Early Vessel Signs Reflect Clot Composition in Acute Stroke
TLDR
CT HMCAS and gradient-echo MRI BA reflect pathology of occlusive thrombus, whereas absence of H MCAS or BA may indicate fibrin-predominant occlusion thrombi.
Identifying stroke in the field. Prospective validation of the Los Angeles prehospital stroke screen (LAPSS).
TLDR
The Los Angeles Prehospital Stroke Screen allows prehospital personnel to identify patients with acute cerebral ischemia and intracerebral hemorrhage with a high degree of sensitivity and specificity.
...
1
2
3
4
5
...