• Publications
  • Influence
Descartes' Error: Emotion, Reason and the Human Brain
TLDR
Brain books are similarly popular: humans are considered from a pathological/laboratory perspective and computer metaphors abound (your mind is your software!) and there are boxes and arrows in profusion. Expand
Behavioural and functional anatomical correlates of deception in humans
TLDR
Lying was associated with longer response times and greater activity in bilateral ventrolateral prefrontal cortices and Ventrolateral cortex may be engaged in generating lies or withholding the truth. Expand
A PET study of voluntary movement in schizophrenic patients experiencing passivity phenomena (delusions of alien control).
TLDR
These hyperactive cerebral regions subserve attention to internal and external bodily space, and the attribution of significance to sensory information, they provide a plausible anatomical substrate for the misattribution of internally generated acts to external entities. Expand
A cognitive neurobiological account of deception: evidence from functional neuroimaging.
An organism may use misinformation, knowingly (through deception) or unknowingly (as in the case of camouflage), to gain advantage in a competitive environment. From an evolutionary perspective,Expand
Investigating the functional anatomy of empathy and forgiveness
Previous functional brain imaging studies suggest that the ability to infer the intentions and mental states of others (social cognition) is mediated by medial prefrontal cortex. Little is knownExpand
Discrete neurophysiological correlates in prefrontal cortex during hysterical and feigned disorder of movement
TLDR
Functional neuroimaging was used to examine the neural correlates of hysterical symptoms and those that are feigned in adults with major depressive disorder and post-traumatic stress disorder. Expand
Pathophysiology of 'positive' thought disorder in schizophrenia.
TLDR
The severity of positive thought disorder was inversely correlated with activity in areas implicated in the regulation and monitoring of speech production, and reduced activity in these regions may contribute to the articulation of the linguistic anomalies that characterisepositive thought disorder. Expand
A functional magnetic resonance imaging study of social cognition in schizophrenia during an acute episode and after recovery.
TLDR
This is the first study to the authors' knowledge to use a social cognition paradigm to reveal improved left medial prefrontal cortex activation in schizophrenia after recovery from an acute episode, and results suggest that restored left medial cortex activation may mediate improvement of insight and social functioning in patients with schizophrenia. Expand
Social cognition, brain networks and schizophrenia
TLDR
Neuroimaging and neuropsychological studies suggest convergence upon specific networks for mindreading and empathy (the temporal cortex, amygdala and the prefrontal cortex) but the frontal lobe is likely to play a central role in enabling social cognition, butMindreading and empathic abilities may require relatively different weighting of subcomponents within the same frontal-temporal social cognition network. Expand
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