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Adjunctive counseling during brief and extended buprenorphine-naloxone treatment for prescription opioid dependence: a 2-phase randomized controlled trial.
Prescription opioid-dependent patients are most likely to reduce opioid use during buprenorphine-naloxone treatment; if tapered off bupreliminary treatment, even after 12 weeks of treatment, the likelihood of an unsuccessful outcome is high, even in patients receiving counseling in addition to SMM. Expand
Cocaine dependence with and without post-traumatic stress disorder: a comparison of substance use, trauma history and psychiatric comorbidity.
Comparisons between individuals with and without lifetime PTSD revealed that individuals with PTSD had significantly higher rates of exposure to traumatic events, earlier age of first assault, more severe symptomatology, andHigher rates of Axis I and Axis II diagnoses. Expand
Sertraline in the treatment of co-occurring alcohol dependence and posttraumatic stress disorder.
There may be subtypes of alcohol-dependent individuals who respond differently to serotonin reuptake inhibitor treatment, and further investigation of differential responders may lead to improvements in the pharmacological treatment of co-occurring alcohol dependence and PTSD. Expand
The Role of Stress in Alcohol Use, Alcoholism Treatment, and Relapse
  • K. Brady, S. Sonne
  • Psychology, Medicine
  • Alcohol research & health : the journal of the…
  • 22 December 1999
In the future, individualized treatment approaches that emphasize stress management strategies in those patients in whom a clear connection between stress and relapse exists will become particularly important. Expand
Gender differences in individuals with comorbid alcohol dependence and post-traumatic stress disorder.
PTSD more often preceded alcohol dependence in women than in men, and women were more likely than men to demonstrate higher rates of other anxiety disorders and test positive for cocaine at treatment entry. Expand
Substance Abuse and Bipolar Affective Disorder
It is suggested that individuals with bipolar affective disorder complicated by substance abuse may have more hospitalizations, a higher incidence of dysphoric mania, earlier onset of mood problems, and more comorbid axis I disorders. Expand
The relationship between substance abuse and bipolar disorder.
Data from several studies indicate that the presence of a substance use disorder may be a predictor of poor response to lithium, and it is possible that the anticonvulsants divalproex sodium and carbamazepine may be more useful in this population of patients with bipolar disorder. Expand
Symptom Improvement in Co-Occurring PTSD and Alcohol Dependence
Examination of the temporal course of symptom improvement revealed that alcohol symptoms tended to start improving either before or in conjunction with PTSD symptoms, and that PTSD treatment may be important to optimizing outcomes for patients with comorbid PTSD and alcohol dependence. Expand
Patient characteristics associated with buprenorphine/naloxone treatment outcome for prescription opioid dependence: Results from a multisite study.
This is the first study to examine characteristics associated with treatment outcome in patients dependent exclusively on prescription opioids, and some that have previously been found to predict heroin-dependent patients' response to methadone treatment and some specific to prescription opioid- dependent patients receiving buprenorphine/naloxone treatment. Expand
Smoking cessation treatment in community-based substance abuse rehabilitation programs.
Smoking cessation treatment resulted in significant reductions in daily smoking and modest smoking abstinence rates without having an adverse impact on substance abuse rehabilitation when given concurrently with outpatient substance abuse treatment. Expand