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- Publications
- Influence
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
- V. Raj, H. Mou, +13 authors B. Haagmans
- Biology, Medicine
- Nature
- 13 March 2013
Most human coronaviruses cause mild upper respiratory tract disease but may be associated with more severe pulmonary disease in immunocompromised individuals. However, SARS coronavirus caused severe… Expand
Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study
- C. Reusken, B. Haagmans, +21 authors M. Koopmans
- Biology, Medicine
- The Lancet Infectious Diseases
- 9 August 2013
Summary
Background
A new betacoronavirus—Middle East respiratory syndrome coronavirus (MERS-CoV)—has been identified in patients… Expand
Novel Hepatitis E Virus in Ferrets, the Netherlands
- V. Raj, S. Smits, +4 authors B. Haagmans
- Medicine, Biology
- Emerging infectious diseases
- 1 August 2012
To the Editor: Hepatitis E virus (HEV), a member of the family Hepeviridae and the genus Hepevirus, is transmitted by the fecal–oral route and causes liver inflammation, which leads to mortality… Expand
Adenosine Deaminase Acts as a Natural Antagonist for Dipeptidyl Peptidase 4-Mediated Entry of the Middle East Respiratory Syndrome Coronavirus
- V. Raj, S. Smits, +11 authors B. Haagmans
- Biology, Medicine
- Journal of Virology
- 20 November 2013
ABSTRACT Middle East respiratory syndrome coronavirus (MERS-CoV) replicates in cells of different species using dipeptidyl peptidase 4 (DPP4) as a functional receptor. Here we show the resistance of… Expand
Exacerbated Innate Host Response to SARS-CoV in Aged Non-Human Primates
- S. Smits, A. de Lang, +8 authors B. Haagmans
- Biology, Medicine
- PLoS pathogens
- 1 February 2010
The emergence of viral respiratory pathogens with pandemic potential, such as severe acute respiratory syndrome coronavirus (SARS-CoV) and influenza A H5N1, urges the need for deciphering their… Expand
An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels
- B. Haagmans, J. van den Brand, +14 authors A. Osterhaus
- Biology, Medicine
- Science
- 1 January 2016
Coronaviruses in the Middle East Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe acute respiratory illness and kills about a third of people infected. The virus is common in… Expand
Human Coronavirus EMC Does Not Require the SARS-Coronavirus Receptor and Maintains Broad Replicative Capability in Mammalian Cell Lines
- M. Müller, V. Raj, +16 authors C. Drosten
- Biology, Medicine
- mBio
- 11 December 2012
ABSTRACT A new human coronavirus (hCoV-EMC) has emerged very recently in the Middle East. The clinical presentation resembled that of the severe acute respiratory syndrome (SARS) as encountered… Expand
Virus genomes reveal factors that spread and sustained the Ebola epidemic
- G. Dudas, L. M. Carvalho, +93 authors A. Rambaut
- Biology, Medicine
- Nature
- 20 April 2017
TLDR
Human Picobirnaviruses Identified by Molecular Screening of Diarrhea Samples
- M. van Leeuwen, M. M. W. Williams, P. Koraka, J. H. Simon, S. Smits, A. Osterhaus
- Biology, Medicine
- Journal of Clinical Microbiology
- 24 March 2010
ABSTRACT The global threat of (re)emerging infectious viruses requires a more effective approach regarding virus surveillance and diagnostic assays, as current diagnostics are often virus species… Expand
Detection of novel divergent arenaviruses in boid snakes with inclusion body disease in The Netherlands.
- R. Bodewes, M. Kik, +4 authors A. Osterhaus
- Biology, Medicine
- The Journal of general virology
- 1 June 2013
Arenaviruses are bi-segmented negative-stranded RNA viruses, which were until recently only detected in rodents and humans. Now highly divergent arenaviruses have been identified in boid snakes with… Expand
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