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Quantitative detection of periodontal pathogens using real-time polymerase chain reaction with TaqMan probes.
- M. Kuboniwa, A. Amano, +6 authors S. Shizukuishi
- Biology, Medicine
- Oral microbiology and immunology
- 1 June 2004
Quantitative analysis, with identification of periodontopathic bacteria, is important for the diagnosis, therapeutic evaluation and risk assessment of periodontal disease. We developed a highly… Expand
Relationship of serum advanced glycation end products with deterioration of periodontitis in type 2 diabetes patients.
BACKGROUND A close relationship between diabetes and chronic periodontitis has been demonstrated. We previously found that Porphyromonas gingivalis with the type II fimA gene is an infectious factor… Expand
Relationship of Porphyromonas gingivalis with glycemic level in patients with type 2 diabetes following periodontal treatment.
INTRODUCTION The aim of this study was to assess the relationship between serum glycemic levels and subgingival microbial profile alteration following periodontal treatment in patients with type 2… Expand
Longitudinal study of the association between smoking as a periodontitis risk and salivary biomarkers related to periodontitis.
- Miyuki Kibayashi, M. Tanaka, +6 authors S. Shizukuishi
- Journal of periodontology
- 30 April 2007
BACKGROUND Insufficient data exist regarding the long-term influence of lifestyle factors including smoking on periodontal health. The objective of this study was to examine the prospective… Expand
Determination of smoking and obesity as periodontitis risks using the classification and regression tree method.
BACKGROUND A model that focuses on personal risk factors associated with poor lifestyle has been proposed for the etiology of generalized periodontitis. Numerous investigations have linked individual… Expand
Involvement of minor components associated with the FimA fimbriae of Porphyromonas gingivalis in adhesive functions.
- S. Nishiyama, Y. Murakami, H. Nagata, S. Shizukuishi, I. Kawagishi, F. Yoshimura
- Biology, Medicine
- 1 June 2007
The FimA fimbriae of Porphyromonas gingivalis, the causative agent of periodontitis, have been implicated in various aspects of pathogenicity, such as colonization, adhesion and aggregation. In this… Expand
Association between passive and active smoking evaluated by salivary cotinine and periodontitis.
- Y. Yamamoto, N. Nishida, +5 authors S. Shizukuishi
- Journal of clinical periodontology
- 1 October 2005
AIM This study attempted to determine the relationship between passive and active smoking on the basis of salivary cotinine levels and periodontitis severity. METHODS Japanese workers (n=273) were… Expand
Relationship between periodontal disease status and combination of biochemical assays of gingival crevicular fluid.
- T. Hanioka, R. Matsuse, Yukiko Shigemoto, M. Ojima, S. Shizukuishi
- Journal of periodontal research
- 1 August 2005
BACKGROUND Currently, no biochemical assay involving gingival crevicular fluid is utilized routinely as a screening test for periodontal disease. OBJECTIVE The objective of the present study was to… Expand
P. gingivalis accelerates gingival epithelial cell progression through the cell cycle.
- M. Kuboniwa, Y. Hasegawa, +4 authors Ozlem Yilmaz
- Biology, Medicine
- Microbes and infection
- 1 February 2008
P. gingivalis, an opportunistic pathogen in periodontal disease, can reside within the epithelial cells that line the gingival crevice. A proteomic analysis revealed that infection of gingival… Expand
Glyceraldehyde-3-Phosphate Dehydrogenase of Streptococcus oralis Functions as a Coadhesin for Porphyromonas gingivalis Major Fimbriae
ABSTRACT Cohesive interactions between Porphyromonas gingivalis and plaque-forming bacteria, such as Streptococcus oralis, are considered to play an important role in the colonization of P.… Expand