• Publications
  • Influence
Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency
Objective Pro-opiomelanocortin (POMC)-derived peptides act on neurons expressing the Melanocortin 4 receptor (MC4R) to reduce body weight. Setmelanotide is a highly potent MC4R agonist that leads toExpand
  • 64
  • 8
Improvement in physical and chemical properties of sodic soil by 3, 6 and 9 years old plantation of Eucalyptus tereticornis Biorejuvenation of sodic soil
Abstract A field experiment was carried out in Ramshahpur and Chandauki villages of Sultanpur district, India with the objective of assessing changes undergone by soil characteristics of sodicExpand
  • 99
  • 6
Role of glutathione in the metabolism-dependent toxicity and chemotherapy of cyclophosphamide.
The role of glutathione in the biological effects of cyclophosphamide (CP) was evaluated by investigating the following: effect of CP on hepatic glutathione levels; relationship between hepaticExpand
  • 121
  • 5
  • PDF
Melanocortin Antagonists Define Two Distinct Pathways of Cardiovascular Control by α- and γ-Melanocyte-Stimulating Hormones
Melanocortin peptides and at least two subtypes of melanocortin receptors (MC3-R and MC4-R) are present in brain regions involved in cardiovascular regulation. In urethane-anesthetized rats,Expand
  • 130
  • 5
  • PDF
Western Blot analysis of the antigens of Toxoplasma gondii recognized by human IgM and IgG antibodies.
Western Blot analysis revealed that both IgM and IgG antibodies present in the sera of humans infected with Toxoplasma gondii recognize three major antigens with apparent m.w. of 32,000, 22,000, andExpand
  • 209
  • 3
In vivo recombinant interleukin 2 administration enhances survival against a lethal challenge with Toxoplasma gondii.
Administration of recombinant interleukin 2 (rIL 2) resulted in a significant (p less than 0.01) decrease in mortality in mice infected with a dose of Toxoplasma gondii that killed 100% of untreatedExpand
  • 108
  • 3
Regional chemotherapy via the pulmonary artery for pulmonary metastases
Regional chemotherapy with Adriamycin via the pulmonary artery produces significantly higher tissue levels in the infused canine lobe than systemic administration. Seven patients with soft tissueExpand
  • 18
  • 3
Melanocortin antagonists define two distinct pathways of cardiovascular control by alpha- and gamma-melanocyte-stimulating hormones.
Melanocortin peptides and at least two subtypes of melanocortin receptors (MC3-R and MC4-R) are present in brain regions involved in cardiovascular regulation. In urethane-anesthetized rats,Expand
  • 28
  • 3
The Influence of Acupuncture Stimulation During Pregnancy: The Induction and Inhibition of Labor
Uterine response to electroacupuncture stimulation of specific sites of the extremities is demonstrated in 60 pregnant women— 48 cases for labor induction and 12 cases for inhibition of prematureExpand
  • 58
  • 2
MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency
Genetic defects underlying the melanocortin-4 receptor (MC4R) signaling pathway lead to severe obesity. Three severely obese LEPR-deficient individuals were administered the MC4R agonistExpand
  • 76
  • 2