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Report of the International Workshop on Screening for Breast Cancer.
BACKGROUND Over the past 30 years, eight major randomized controlled trials of breast cancer screening--with mammography and/or clinical breast examination--have been conducted. Results from several
Multivitamin supplementation and risk of birth defects.
The hypothesis that periconceptional vitamin supplementation may extend benefits beyond a reduction in NTD risk is supported, and it is not clear what nutrient or combination of nutrients might affect risk of other specific defects.
Periconceptional folic acid exposure and risk of occurrent neural tube defects.
Findings suggest that daily periconceptional intake of 0.4 mg of folic acid reduces the risk of occurrent NTDs by approximately 60%.
A case-control study of oral contraceptive use and invasive epithelial ovarian cancer.
The present data confirm previous reports of an inverse association of ovarian cancer risk with oral contraceptive use of several years in duration and suggest that the association may persist for as long as two decades and that it is not confined to any particular type of oral contraceptive formulation.
A hypothesis: nonsteroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer.
The present data suggest that the sustained use of NSAIDs reduces the incidence of human large-bowel cancer.
Prepregnant weight in relation to risk of neural tube defects.
The risk of NTDs increased with increasing prepregnant weight, independent of the effects of folate intake, in women in the greater metropolitan areas of Boston, Mass and Philadelphia, Pa.
Selection, follow-up, and analysis in the Health Insurance Plan Study: a randomized trial with breast cancer screening.
Results of follow-up, 16 years after entry, indicate that mortality due to breast cancer continues to be lower among study women than controls, and the differential has been stable; relatively, it has decreased.
Nonsteroidal anti-inflammatory drugs and risk of digestive cancers at sites other than the large bowel.
Regular continuing nonsteroidal anti-inflammatory drug (NSAID) use has been associated with a reduction in risk of large bowel cancer in many studies, and data suggest that regular continuing NSAID use may be associated with reduced risk of stomach cancer.