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The diagnosis of growth hormone deficiency in children and adults.
I. Introduction II. GHD in Children A. Clinical aspects B. Radiology C. GH provocative tests D. Physiological assessment of GH secretion E. IGFs F. IGFBPs G. Newer strategies for assessment of GHExpand
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International Society for Pediatric and Adolescent Diabetes
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Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society Clinical Practice Guideline.
OBJECTIVE The objective is to provide guidelines for the evaluation and treatment of adults with GH deficiency (GHD). PARTICIPANTS The chair of the Task Force was selected by the ClinicalExpand
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Spermatogenesis after cancer treatment: damage and recovery.
Treatment with cytotoxic chemotherapy and radiotherapy is associated with significant gonadal damage in men, and alkylating agents are the most common agents implicated. The vast majority of menExpand
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Hypopituitarism following external radiotherapy for pituitary tumours in adults.
The development of anterior pituitary hormone deficiencies has been studied in a group of 165 patients who underwent external radiotherapy for tumours of the pituitary or closely related anatomicalExpand
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Consensus statement on the management of the GH-treated adolescent in the transition to adult care.
The European Society for Paediatric Endocrinology held a consensus workshop in Manchester, UK in December 2003 to discuss issues relating to the care of GH-treated patients in the transition fromExpand
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The severity of growth hormone deficiency in adults with pituitary disease is related to the degree of hypopituitarism
OBJECTIVE A number of studies of the effect of GH replacement therapy in adult patients with GH deficlency have been published, but the definition of GH deficiency has varied considerably. In orderExpand
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Isolation of germ cells from human testicular tissue for low temperature storage and autotransplantation.
OBJECTIVE To develop a new protocol for conserving fertile potential in men undergoing sterilizing chemotherapy by low temperature banking of germ cells which can be returned to the patient's testesExpand
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The prevalence and characteristics of colorectal neoplasia in acromegaly.
An increased prevalence of colorectal neoplasia has been reported in acromegalic patients, and recommendations have been made for early colonoscopic screening and regular surveillance. ThisExpand
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Response: More About: Prospective Study of Colorectal Cancer Risk in Men and Plasma Levels of Insulin-Like Growth Factor (IGF)-I and IGF- Binding Protein-3
Background: Insulin-like growth factor-I (IGF-I) is a potent mitogen for normal and neoplastic cells, whereas IGF-binding protein-3 (IGFBP-3) inhibits cell growth in many experimental systems.Expand
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