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Glycemic control, dyslipidemia and endothelial dysfunction in coexisted diabetes, hypertension and nephropathy.
Results indicate a clear relationship of declining renal function with poor glycemic control, abnormal lipid metabolism, endothelial dysfunction and initiation of acute phase response in tissues affected from the microvascular complications of diabetes like hypertension and nephropathy.
Protective Effects of Salivary Factors in Dental Caries in Diabetic Patients of Pakistan
It is concluded that the suitable salivary pH and flow rate may be regarded as main protective factors against dental caries in diabetes.
Association of SNP rs9939609 in FTO gene with metabolic syndrome in type 2 diabetic subjects, rectruited from a tertiary care unit of Karachi, Pakistan
The FTO rs9939609 SNP was associated with an increased risk for Metabolic Syndrome in type 2 diabetic populations at a tertiary care unit of Karachi, Pakistan.
Dental caries in diabetes mellitus: role of salivary flow rate and minerals.
Optimum salivary flow rate is responsible for establishing protective environment against dental caries and adequate level of calcium, phosphate, and fluoride is also involved in significant deposition of these minerals in plaque, which greatly reduces the development of caries in the adjacent enamel of teeth.
Common variant within the FTO gene, rs9939609, obesity and type 2 diabetes in population of Karachi, Pakistan.
In the study population of South Asian ancestry, variants of the FTO gene predispose to type 2 diabetes, but not entirely through their effect on BMI.
The association of GSTM1 and GSTT1 polymorphisms with squamous cell carcinoma of cervix in Pakistan
It is suggested that GSTM1 null genotype in cervical cell samples may be associated with more severe precancerous lesions of the cervix.
Angiotensin converting enzyme (ACE) gene expression in experimentally induced liver cirrhosis in rats.
The finding of major up-regulation of ACE in the experimental rat liver provides further insight into the complexities of the RAS and its regulation in liver injury.
Correlation Between Frequent Risk Factors of Diabetic Nephropathy and Serum Sialic Acid
Elevated serum sialic acid level is strongly associated with the presence of nephropathy, a microvascular complications of diabetes, a major risk factor in the ______________________________ received on: 3/5/06 Accepted on: 30/11/06 Correspondence to: Dr. Tabassum Mahboob, Department of Biochemistry, University of Karachi, Karachi – 75270, Pakistan.
Protective effect of green tea on CCl 4 induced hepatoxicity in experimental rats
weeks+5% oral administration of green tea. The preventive effects of green tea were measured by means of plasma alanine aminotransferase (ALT), alkaline phosphatase (ALP), total and direct bilirubin,