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  • S. A. Chowdhury, S. Shackney, K. Heselmeyer-Haddad, T. Ried, A. Schäffer, R. Schwartz
  • Biology, Medicine, Computer Science
  • PLoS Computational Biology
  • 2014 (First Publication: 1 July 2014)
  • We present methods to construct phylogenetic models of tumor progression at the cellular level that include copy number changes at the scale of single genes, entire chromosomes, and the whole genome.Expand
  • S. A. Chowdhury, S. Shackney, K. Heselmeyer-Haddad, T. Ried, A. Schäffer, R. Schwartz
  • Computer Science, Medicine, Biology
  • Bioinform.
  • 2013 (First Publication: 19 June 2013)
  • Motivation: Development and progression of solid tumors can be attributed to a process of mutations, which typically includes changes in the number of copies of genes or genomic regions. AlthoughExpand