S. Scott

Publications135
h-index18
Citations832
Highly Influential Citations25
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What caused the Black Death?
TLDR
Evidence is presented that the Black Death was a viral haemorrhagic fever, characterised by a long incubation period of 32 days, which allowed it to be spread widely even with the limited transport of the Middle Ages.
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Reappraisal of the historical selective pressures for the CCR5-Δ32 mutation
TLDR
It is suggested that the original single mutation appeared over 2500 years ago and that persistent epidemics of a haemorrhagic fever that struck at the early classical civilisations served to force up the frequency to about 5×10−5 at the time of the Black Death in 1347.
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Return of the Black Death: The World's Greatest Serial Killer
TLDR
A chronology of key events: the birth of a serial killer, the surprising link between AIDS and the Black Death, and the dangers of emergent diseases.
Biology of Plagues: Evidence from Historical Populations
1. Introduction 2. Epidemiological concepts 3. The biology of bubonic plague 4. The Great Pestilence 5. Case study: the plague at Penrith in 1597-98 6. Pestilence and plague in the 16th century in…
Oscillatory dynamics of smallpox and the impact of vaccination.
TLDR
The evolution of smallpox epidemics in London, 1647-1893, was studied by time series analysis of deaths from the disease in the Bills of Mortality and the dynamics of the disease can now be described by an SEIR model: severe outbreaks ofSmallpox are followed by decaying epidemics.
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The dynamics of measles epidemics.
TLDR
A linearised model of the dynamics of epidemics shows that T is determined by the product of population (N) and susceptibility (beta) and that the system will settle at its steady state unless the epidemics are driven.
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The dynamics of smallpox epidemics in Britain, 1550–1800
TLDR
Time-series analysis was used to determine the periodicity of smallpox epidemics during the seventeenth and eighteenth centuries in two contrasting representative situations: London, a large city where smallpox was endemic, and Penrith, a small rural town.
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The dynamics of scarlet fever epidemics in England and Wales in the 19th century
Summary There was a marked rise in scarlet fever mortality in England and Wales in the mid-nineteenth century and spectral analysis of the registration details, 1847–80, shows that the interepidemic…
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Reappraisal of the historical selective pressures for the CCR5-Delta32 mutation.
TLDR
It is suggested that the original single mutation appeared over 2500 years ago and that persistent epidemics of a haemorrhagic fever that struck at the early classical civilisations served to force up the frequency to about 5x10(-5) at the time of the Black Death in 1347.
View on PubMed
The plague in Penrith, Cumbria, 1597/8: its causes, biology and consequences.
TLDR
Using a family reconstitution study the biology of the plague in Penrith, Cumbria in 1597/8 is described in detail, showing that bubonic plague was not the causative agent, and the possibility that anthrax was responsible for the drastic mortality.
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