• Publications
  • Influence
Clinical review: Update on hemodynamic monitoring - a consensus of 16
Hemodynamic monitoring plays a fundamental role in the management of acutely ill patients. With increased concerns about the use of invasive techniques, notably the pulmonary artery catheter, toExpand
  • 285
  • 20
  • PDF
Acute Respiratory Distress Syndrome: Pathophysiology and Therapeutic Options
Acute Respiratory Distress Syndrome (ARDS) is a common entity in critical care. ARDS is associated with many diagnoses, including trauma and sepsis, can lead to multiple organ failure and has highExpand
  • 113
  • 11
  • PDF
Microcirculatory Alterations in Patients With Severe Sepsis: Impact of Time of Assessment and Relationship With Outcome*
Objectives:Sepsis induces microvascular alterations that may play an important role in the development of organ dysfunction. However, the relationship of these alterations to systemic variables andExpand
  • 321
  • 9
  • PDF
Myocardial depression in sepsis: from pathogenesis to clinical manifestations and treatment.
The cardiovascular system plays a key role in sepsis, and septic myocardial depression is a common finding associated with increased morbidity and mortality. Myocardial depression during sepsis isExpand
  • 150
  • 6
Can changes in arterial pressure be used to detect changes in cardiac index during fluid challenge in patients with septic shock?
PurposeResponse to fluid challenge is often defined as an increase in cardiac index (CI) of more than 10–15%. However, in clinical practice CI values are often not available. We evaluated whetherExpand
  • 101
  • 6
Predicting transfusions in cardiac surgery: the easier, the better: the Transfusion Risk and Clinical Knowledge score
Background and Objectives  Allogeneic blood products transfusions are associated with an increased morbidity and mortality risk in cardiac surgery. At present, a few transfusion risk scores have beenExpand
  • 59
  • 5
Cardiac output monitoring by pressure recording analytical method in cardiac surgery.
OBJECTIVE A less-invasive method has been developed that may provide an alternative to monitor cardiac output from arterial pressure: beat-to-beat values of cardiac output can be obtained by pressureExpand
  • 73
  • 5
suPAR as a prognostic biomarker in sepsis
Sepsis is the clinical syndrome derived from the host response to an infection and severe sepsis is the leading cause of death in critically ill patients. Several biomarkers have been tested for useExpand
  • 106
  • 4
  • PDF
Perioperative use of tirofiban hydrochloride (Aggrastat) does not increase surgical bleeding after emergency or urgent coronary artery bypass grafting.
BACKGROUND The platelet glycoprotein IIb/IIIa inhibitor tirofiban hydrochloride improves outcome in patients with acute coronary syndrome. Nevertheless, a considerable number of patients requireExpand
  • 91
  • 4
Acute kidney injury after cardiac arrest
IntroductionThe aim of this study was to evaluate the incidence and determinants of AKI in a large cohort of cardiac arrest patients.MethodsWe reviewed all patients admitted, for at least 48 hours,Expand
  • 71
  • 4