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The chemistry and biological activity of the Hyacinthaceae.
TLDR
The phytochemical profiles of 38 genera of the Hyacinthaceae will be discussed as well as any biological activity associated with both crude extracts and compounds isolated, and the current contribution considers the family at a global level.
Bioactive compounds from Combretum erythrophyllum.
TLDR
Bioassay-guided fractionation of a methanol extract of Combretum erythrophyllum yielded two known bioactive compounds, combretastatin A-1 and (-)-combretASTatin, and two new bioactive glucosides.
Melanin Production Inhibitors from the West African Cassipourea congoensis
TLDR
The crude extract and compounds 1 and 5 were found to inhibit the production of melanin at 10 µM with low cytotoxicity validating the ethnomedicinal use of this plant.
Antimalarial activity of plant metabolites.
This review covers the structures of compounds with antiplasmodial activity isolated from plants and is organized according to plant family. A total of 170 structures has been reviewed from 186
Antimalarial activity of plant metabolites.
This review covers the structures of compounds with antiplasmodial activity isolated from plants and is organized according to plant family. A total of 170 structures has been reviewed from 186
Antiangiogenic Activity and Cytotoxicity of Triterpenoids and Homoisoflavonoids from Massonia pustulata and Massonia bifolia.
TLDR
The dichloromethane extract of the bulbs of Massonia pustulata yielded two known homoisoflavonoids and two previously unreported triterpenoid derivatives, suggesting antiangiogenic activity against human retinal microvascular endothelial cells.
The Antiangiogenic Activity of Naturally Occurring and Synthetic Homoisoflavonoids from the Hyacinthaceae ( sensu APGII).
TLDR
Several compounds showed interesting antiproliferative and antiangiogenic activities in vitro on retinal microvascular endothelial cells, a disease-relevant cell type, with the synthetic chromane, 46, showing the best activity.
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