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Hypoxic preconditioning with cobalt ameliorates hypobaric hypoxia induced pulmonary edema in rat.
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Effect of Subchronic Hypobaric Hypoxia on Oxidative Stress in Rat Heart
TLDR
The data suggests a reciprocal regulation of ROS and NO and this effect is mediated by the increase in antioxidant proteins HO-1 and MT, which plays an important role in acclimatization.
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Hypoxia preconditioning by cobalt chloride enhances endurance performance and protects skeletal muscles from exercise‐induced oxidative damage in rats
TLDR
Training under hypoxia has several advantages over normoxic training in terms of enhancing the physical performance and protection against exercise‐induced oxidative damage in the skeletal muscles and improvement of physical performance is tested.
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Hypoxic preconditioning facilitates acclimatization to hypobaric hypoxia in rat heart
TLDR
Acute systemic hypoxia induces delayed cardioprotection against ischaemia‐reperfusion injury in the heart and cobalt chloride is hypothesized that this chemical would mimic the preconditioning effect and facilitate acclimatization to hypobaric Hypoxia in rat heart.
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Identification of haptoglobin and apolipoprotein A-I as biomarkers for high altitude pulmonary edema
TLDR
The data conclusively shows that two proteins, haptoglobin and apolipoprotein A-I are upregulated in plasma of HAPE patients, suggesting that these proteins may provide a fast and effective control of inflammatory damage until the subsequent mechanisms can begin to operate.
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Hypoxic preconditioning with cobalt attenuates hypobaric hypoxia-induced oxidative damage in rat lungs.
TLDR
It is concluded that HPC with cobalt enhances antioxidant status in the lung and protects from subsequent hypobaric hypoxia-induced oxidative stress.
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Augmentation of aerobic respiration and mitochondrial biogenesis in skeletal muscle by hypoxia preconditioning with cobalt chloride.
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Preconditioning effect of cobalt chloride supplementation on hypoxia induced oxidative stress in male albino rats
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Expression of Monocarboxylate Transporter Isoforms in Rat Skeletal Muscle Under Hypoxic Preconditioning and Endurance Training.
TLDR
Almost all MCTs are expressed in red gastrocnemius muscle at the mRNA level and their expression is regulated differently under hypoxia preconditioning and exercise condition.
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COMPUTER-ASSISTED DRUG DESIGNING OF TRIAZOLE DERIVATIVE OF NOSCAPINE AS TUBULIN-BINDING ANTICANCER DRUG
TLDR
Fusion of two novel anticancer compounds with low toxicity, i.e., noscapine and triazole to generate a new ligand derivative found that designed derivative compounds have better efficacy as compared nos capine and Triazole.
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