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Effect of Antisense Oligonucleotides against Cholesteryl Ester Transfer Protein on the Development of Atherosclerosis in Cholesterol-fed Rabbits*
- M. Sugano, N. Makino, A. Mizushima
- BiologyThe Journal of Biological Chemistry
- 27 February 1998
Cholesteryl ester transfer protein (CETP) is the enzyme that facilitates the transfer of cholesteryl ester from high density lipoprotein (HDL) to apolipoprotein B (apoB)-containing lipoproteins.…
Interaction of mRNAs for angiotensin II type 1 and type 2 receptors to vascular remodeling in spontaneously hypertensive rats.
- S. Otsuka, M. Sugano, N. Makino, S. Sawada, T. Hata, Y. Niho
- Biology, MedicineHypertension
- 1 September 1998
TLDR
Low density lipoproteins develop resistance to oxidative modification due to inhibition of cholesteryl ester transfer protein by a monoclonal antibody.
- M. Sugano, S. Sawada, K. Tsuchida, N. Makino, M. Kamada
- BiologyJournal of lipid research
- 2000
TLDR
Intravenous injection with antisense oligodeoxynucleotides against angiotensinogen decreases blood pressure in spontaneously hypertensive rats.
- N. Makino, M. Sugano, S. Ohtsuka, S. Sawada
- Biology, MedicineHypertension
- 1 May 1998
TLDR
Chronic antisense therapy for angiotensinogen on cardiac hypertrophy in spontaneously hypertensive rats.
- N. Makino, M. Sugano, S. Ohtsuka, S. Sawada, T. Hata
- Biology, MedicineCardiovascular research
- 1 December 1999
Secretion of preβ HDL increases with the suppression of cholesteryl ester transfer protein in Hep G2 cells
- S. Sawada, M. Sugano, N. Makino, H. Okamoto, K. Tsuchida
- Biology
- 1 October 1999
Reduction of plasma angiotensin II to normal levels by antisense oligodeoxynucleotides against liver angiotensinogen cannot completely attenuate vascular remodeling in spontaneously hypertensive rats
- M. Sugano, K. Tsuchida, S. Sawada, N. Makino
- Biology, MedicineJournal of hypertension
- 1 June 2000
TLDR
Secretion of prebeta HDL increases with the suppression of cholesteryl ester transfer protein in Hep G2 cells.
- S. Sawada, M. Sugano, N. Makino, H. Okamoto, K. Tsuchida
- BiologyAtherosclerosis
- 1999
TLDR