Heterogeneity of enteroaggregative Escherichia coli virulence demonstrated in volunteers.
All 4 EAggEC isolates showed a modest degree of gentamicin protection in HEp-2 cells, and 042 did not express this fimbria as determined by immunogold electron microscopy and genetic probe hybridization.
A systematic review of ETEC epidemiology focusing on colonization factor and toxin expression.
Evolutionary and Functional Relationships of Colonization Factor Antigen I and Other Class 5 Adhesive Fimbriae of Enterotoxigenic Escherichia coli
It is suggested that the minor subunits of class 5 fimbriae may be superior to whole fimbRIae in inducing antiadhesive immunity.
A sensitive and specific DNA probe to identify enteroaggregative Escherichia coli, a recently discovered diarrheal pathogen.
- B. Baudry, S. Savarino, P. Vial, J. Kaper, M. Levine
- Biology, MedicineJournal of Infectious Diseases
- 1 June 1990
The isolation and cloning of a 1-kilobase fragment from the plasmid ofEAggEC strain 17-2 is described, which should greatly facilitate epidemiologic studies assessing the importance of EAggEC as a diarrheal pathogen.
A Commensal Gone Bad: Complete Genome Sequence of the Prototypical Enterotoxigenic Escherichia coli Strain H10407
This study determined the complete genomic sequence of E. coli H10407, a prototypical strain of enterotoxigenic E.coli, which reproducibly elicits diarrhea in human volunteer studies and provided a genetic context for the vast amount of experimental and epidemiological data that have been published.
Effect of Dengue Serostatus on Dengue Vaccine Safety and Efficacy
CYD‐TDV protected against severe VCD and hospitalization for VCD for 5 years in persons who had exposure to dengue before vaccination, and there was evidence of a higher risk of these outcomes in vaccinated people who had not been exposed to d Dengue.
Pathogenicity and convalescent excretion of Campylobacter in rural Egyptian children.
The observation that natural infection did not confer protection during the first 6 months of life poses a challenge to vaccine development.
Epidemiology of enterotoxigenic Escherichia coli diarrhea in a pediatric cohort in a periurban area of lower Egypt.
Findings indicate that the epidemiologic patterns of LT-only and ST-only ETEC are not identical and that disease interventions should include improved household sanitation, and ownership of a household sanitary latrine, but not breast-feeding, was associated with a lower risk of both enterotoxin phenotypes.
Epidemiology of rotavirus diarrhea in Egyptian children and implications for disease control.
Reliable epidemiologic data are essential for formulating effective policy to control rotavirus disease through immunization. The objective of this study was to describe the epidemiology of rotavirus…
Identification and characterization of a gene cluster mediating enteroaggregative Escherichia coli aggregative adherence fimbria I biogenesis
On the basis of mutational analysis and protein homology data, it is inferred that aggA, aggC, and aggD are involved in biogenesis of AAF/I, encoding a major fimbrial subunit, outer membrane usher, and periplasmic fimbrian chaperone, respectively.