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In vitro evaluation of guar gum as a carrier for colon-specific drug delivery.
TLDR
The results illustrate the usefulness of guar gum as a potential carrier for colon-specific drug delivery and reveal that the use of 4% w/v of rat caecal contents in PBS, obtained after 7 days of enzyme induction provide the best conditions for in vitro evaluation of Guar gum. Expand
Influence of nicorandil on the pharmacodynamics and pharmacokinetics of gliclazide in rats and rabbits
TLDR
The interaction observed appears to be pharmacodynamic at the receptor level as expected and reduced the effect of gliclazide with no significant change in pharmacokinetics when administered in combination. Expand
Antioxidant Activity of the Aqueous Extracts of Spicy Food Additives—Evaluation and Comparison with Ascorbic Acid in In Vitro Systems
TLDR
Strong antioxidant activity of their extracts that was superior to known antioxidant ascorbic acid is revealed and indicate their intake may be beneficial as food additives. Expand
Studies of guar gum compression-coated 5-aminosalicylic acid tablets for colon-specific drug delivery.
TLDR
The study confirmed that selective delivery of 5-ASA to the colon can be achieved using guar gum as a carrier in the form of a compression coating over the drug core. Expand
Influence of aqueous extract of fenugreek-seed powder on the pharmacodynamics and pharmacokinetics of gliclazide in rats/rabbits
TLDR
To evaluate the safety of the herb–drug combination with respect to blood glucose in animal models, Fenugreek-seed powder extract produced hypoglycemia when given alone and prolonged the effect of gliclazide in combination during 1–12 ... Expand
Persistance of Some Insecticides in Chillies
TLDR
An experiment on chillies (variety Pusa jawala) was laid out in randomized block design (RBD) replicated thrice during Kharif 2004 and the residues in harvested red chillies were below detectable levels in all treatments. Expand
Evaluation of the Blood-Glucose Reducing Effects of Aqueous Extracts of the Selected Umbelliferous Fruits Used in Culinary Practices
Purpose: Oxidative stress in diabetes coexists with a reduction in the antioxidant status, which can increase the deleterious effects of free radicals. Many plant extracts and plant products haveExpand
Efficacy of a novel, natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX, niacin-bound chromium and Gymnema sylvestre extract in weight management in human volunteers: a
In this pilot study, the efficacy of a novel, natural extract of a highly bioavailable, calciumpotassium salt of (‐)-hydroxycitric acid (HCA-SX) alone and in combination with a niacin-bound chromiumExpand
In vitro antioxidant assay of selected aqueous plant extracts and their polyherbal formulation
To support the use of selected plant extracts in Ayurveda, naturopathy, the antioxidant potential of the aqueous extract of Vincarosea ( VR ), Gymnemasylvestre ( GS ), Tinosporacordifolia ( TC ) andExpand
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