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Assessing individual interethnic admixture and population substructure using a 48–insertion‐deletion (INSEL) ancestry‐informative marker (AIM) panel
TLDR
The ability to accurately infer interethnic admixtures highlights the usefulness of this marker set for assessing population substructure in association studies, particularly those conducted in Brazilian and other Latin American populations sharing trihybrid ancestry patterns. Expand
Assessment of the Relationship between Self-Declared Ethnicity, Mitochondrial Haplogroups and Genomic Ancestry in Brazilian Individuals
TLDR
It was possible to observe a high degree of heterogeneity in the ancestry for both types of genetic markers, which shows the high genetic admixture that is present in the Brazilian population. Expand
Real-time PCR diagnosis of Plasmodium vivax among blood donors
TLDR
The real-time PCR with TaqMan probes enabled the identification of P. vivax in a high proportion of clinically healthy donors, highlighting the potential risk for transfusion-transmitted malaria. Expand
Study of AZFc partial deletion gr/gr in fertile and infertile Japanese males
TLDR
It is shown that the gr/gr deletion was probably present in the ancestral Y chromosome that entered Japan at least 12,000 years ago, and a new Y chromosome phylogeny for haplogroup D and its derivatives is proposed. Expand
Lack of association between Y chromosome haplogroups and male infertility in Japanese men
TLDR
The data suggest that Y microdeletions and other molecular events causally associated with male infertility in Japan occur independently of the Y chromosome background. Expand
Several Different Lactase Persistence Associated Alleles and High Diversity of the Lactase Gene in the Admixed Brazilian Population
TLDR
The aims of this study were to identify polymorphisms in the MCM6 region associated with the lactase persistence phenotype and to determine the distribution of LCT gene haplotypes in 981 individuals from North, Northeast and South Brazil, which shows a high variability considering the number of L CT haplotypes observed. Expand
Mitochondrial DNA mapping of social-biological interactions in Brazilian Amazonian African-descendant populations
The formation of the Brazilian Amazonian population has historically involved three main ethnic groups, Amerindian, African and European. This has resulted in genetic investigations having beenExpand
Population genetic analysis of insertion-deletion polymorphisms in a Brazilian population using the Investigator DIPplex kit.
TLDR
Comparison of 29 worldwide populations revealed significant genetic differences between continental populations and a closer relationship between the Brazilian and European populations. Expand
Frequency of the Q192R and L55M polymorphisms of the human serum paraoxonase gene (PON1) in ten Amazonian Amerindian tribes
TLDR
It is found that South America Amerindians present the highest frequency of the PON1192*R allele (considered a significant risk factor for heart diseases in some populations) of all the Amerindian and Asian populations so far studied. Expand
SLCO1A2, SLCO1B1 and SLCO2B1 polymorphisms influences chloroquine and primaquine treatment in Plasmodium vivax malaria
TLDR
The present work presents the first pharmacogenetic report of an association between chloroquine/primaquine responses with OATP transporters with a significant interaction between SLCO2B1 genotypes and treatment over time for parasitemia clearance rate on day 2. Expand
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