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Sulpiride: an Antipsychotic with Selective Dopaminergic Antagonist Properties
Objective: To review the pharmacology, pharmacokinetics, clinical investigations, and adverse effects of sulpiride as a treatment for schizophrenia. Data Sources: Information was selected from aExpand
Clozapine: A Novel Antipsychotic Agent
Clozapine is an antipsychotic without the extrapyramidal adverse effects associated with currently marketed antipsychotics. In animals, this drug has not been shown to induce catalepsy and onlyExpand
Availability of insulin from parenteral nutrient solutions.
The effect of the following variables on insulin loss from total parenteral nutrient solutions was examined: (1) time of infusion sample; (2) insulin concentration; (3) amino acid or polypeptideExpand
Diazepam in Tardive Dyskinesia
Tardive dyskinesia, a syndrome of involuntary motor movements, can be a permanent consequence of the long-term use of antipsychotic drugs. While there is no well-established drug treatment, caseExpand
Behavioral changes following generic thioridazine.
Effect of Mylanta on Naproxen Bioavailability
Summary The effect of Mylanta on naproxen bioavailability was studied in 11 healthy volunteers. In separate experiments, single oral doses of naproxen (250 mg) and multiple oral doses (250 mg twiceExpand
Paroxetine: A Selective Serotonin Reuptake Inhibiting Antidepressant
OBJECTIVE: To review the pharmacology, pharmacokinetics, clinical investigations, adverse effects, and dosing strategies of paroxetine as a treatment of major depression. DATA SOURCES: SpecificExpand
Diazepam-induced changes in tardive dyskinesia: suggestions for a new conceptual model.
Using an ABA' research design, the effects of a benzodiazepine gamma-aminobutyric acid (GABA)-ergic agent, diazepam, on various aspects of tardive dyskinesia (TD) were investigated in 21 patients.Expand
Effect of hemodialysis on plasma naproxen concentration.
A case describing the effect of hemodialysis on naproxen plasma levels in a 48-year-old anuric man with chronic glomerulonephritis is reported. The patient received 500 mg of naproxen daily forExpand
Amoxapine (Asendin, Lederle Laboratories)
Amoxapine is a tricyclic antidepressant agent, which is chemically related to the antipsychotic agent loxapine, but which appears to block selectively the neuronal reuptake of norepinephrine; it isExpand