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Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults
TLDR
The results of this study indicate that type 2 diabetes in humans is associated with compositional changes in intestinal microbiota and the level of glucose tolerance should be considered when linking microbiota with metabolic diseases such as obesity and developing strategies to control metabolic diseases by modifying the gut microbiota.
454 pyrosequencing analyses of bacterial and archaeal richness in 21 full-scale biogas digesters.
TLDR
The microbial community of 21 full-scale biogas reactors was examined using 454 pyrosequencing of 16S rRNA gene sequences and revealed that methane formation from acetate takes place mainly via syntrophic acetate oxidation in the CD reactors.
Ecosystem response of pasture soil communities to fumigation-induced microbial diversity reductions: an examination of the biodiversity-ecosystem function relationship
TLDR
Although fumigation reduced soil microbial biodiversity, there was evidence to suggest that it selected for organisms with particular physiological characteristics, and specific functional parameters may be a more sensitive indicator of environmental change than general parameters.
Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
TLDR
This work presents a method, based on binning co-abundant genes across a series of metagenomic samples, that enables comprehensive discovery of new microbial organisms, viruses and co-inherited genetic entities and aids assembly of microbial genomes without the need for reference sequences.
Studying plasmid horizontal transfer in situ: a critical review
This review deals with the prospective, experimental documentation of horizontal gene transfer (HGT) and its role in real-time, local adaptation. We have focused on plasmids and their function as an
Critical Assessment of Metagenome Interpretation—a benchmark of metagenomics software
TLDR
Assembly and genome binning programs performed well for species represented by individual genomes but were substantially affected by the presence of related strains, and parameter settings markedly affected performance, underscoring their importance for program reproducibility.
Conjugative plasmids: vessels of the communal gene pool
TLDR
The term supergenome is used to describe the set of all genes that a prokaryotic ‘individual’ can draw on within a particular environmental setting to obtain adaptability and functional diversity that alleviates the need for large genomes of specialized ‘private genes’.
Enhanced Biofilm Formation and Increased Resistance to Antimicrobial Agents and Bacterial Invasion Are Caused by Synergistic Interactions in Multispecies Biofilms
TLDR
It is strongly indicated that synergistic effects promote biofilm biomass and resistance of the biofilm to antimicrobial agents and bacterial invasion in multispecies biofilms.
Substrate specificity of the OqxAB multidrug resistance pump in Escherichia coli and selected enteric bacteria.
TLDR
The plasmid-encoded OqxAB pump has a wide substrate specificity and can be transferred between Enterobacteriaceae conferring reduced susceptibility to a multitude of substrates, which could indicate some dependence on the outer membrane proteins present in the different species.
Nitrogenase Gene Amplicons from Global Marine Surface Waters Are Dominated by Genes of Non-Cyanobacteria
TLDR
The study indicates that non-cyanobacteria account for a substantial part of the nifH gene pool in marine surface waters and that these genes are at least occasionally expressed and suggest that these bacteria are ecologically significant.
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