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Antiplasmodial and antimycobacterial cyclopeptide alkaloids from the root of Ziziphus mauritiana.
Investigation of the MeOH extract obtained from the root of the Ziziphus mauritiana grown in Thailand resulted in the isolation of two 14- and 13-membered cyclic alkaloids, which exhibited potent antiplasmodial activity against the parasite Plasmodium falciparum. Expand
Bioactive compounds from Bauhinia purpurea possessing antimalarial, antimycobacterial, antifungal, anti-inflammatory, and cytotoxic activities.
Antimycobacterial, antimalarial, antifungal, cytotoxic, and anti-inflammatory activities of the isolated compounds are reported, and biosynthetic pathways of these compounds are also discussed. Expand
Bioactive Metabolites from Spilanthes acmella Murr.
These findings demonstrate for the first time the potential benefits of this medicinal plant as a rich source of high therapeutic value compounds for medicines, cosmetics, supplements and as a health food. Expand
High therapeutic potential of Spilanthes acmella: A review
Considering data from the literature, it could be demonstrated that S. acmella possesses diverse bioactive properties and immense utilization in medicine, health care, cosmetics and as health supplements. Expand
Determination and variation of three active diterpenoids in Andrographis paniculata (Burm.f.) Nees.
There was a large variation of the three active diterpenoids in different A. paniculata products obtained from Thai markets and the results indicated that the amounts of these active compounds consumed, based on the recommended daily doses, from materials obtained from the different suppliers will be different. Expand
Prenylated flavanones from Derris reticulata
Two new pyranoflavanones, 2‴,3‴-epoxylupinifolin and dereticulatin, together with the known flavonoid lupInifolin, were identified from the stems of Derris reticulata and showed cytotoxic activity in the P-388 cell line. Expand
New bioactive triterpenoids and antimalarial activity of Diospyros rubra Lec.
Data is provided to support the medicinal importance of the D. rubra extracts and shows they were only shown to be active antimalarials. Expand
Cyanogenic and non-cyanogenic glycosides from Manihot esculenta.
In addition to lotaustralin and linamarin, a novel cyanogenic glycoside, 2-((6-O-(beta-D-apiofuranosyl)-beta-D-glucopyranosyl)oxy)-2-met hylbutanenitrile , two novel non-cyanogenic glycosides,Expand
Chrysin overcomes TRAIL resistance of cancer cells through Mcl-1 downregulation by inhibiting STAT3 phosphorylation.
The potential of chrysin in overcoming TRAIL resistance of cancer cells is shown and the mechanism of action is elucidated, which involves inhibiting STAT3 and downregulating Mcl-1 gene expression. Expand
Inhibitory effect of Andrographis paniculata extract and its active diterpenoids on platelet aggregation.
The results indicate that the standardized A. paniculata extract may contain other antiplatelet compounds rather than AP(1) and AP(3), which contribute to highAntiplatelet activity, and should be used with caution by patients with bleeding disorders. Expand