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Modulation of drought resistance by the abscisic acid receptor PYL5 through inhibition of clade A PP2Cs.
TLDR
This work indicates that PYL5 is a cytosolic and nuclear ABA receptor that activates ABA signaling through direct inhibition of clade A PP2Cs, and shows that enhanced resistance to drought can be obtained through Pyl5-mediated inhibition ofClade APP2Cs.
Protein Phosphatases 2C Regulate the Activation of the Snf1-Related Kinase OST1 by Abscisic Acid in Arabidopsis[W]
TLDR
Evidence that PP2Cs are directly implicated in the ABA-dependent activation of OST1 is provided and the activation mechanism of AMPK/Snf1-related kinases through the inhibition of regulating PP2C is conserved from plants to human.
Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues
TLDR
The experiments show that the HFH-11 transcription factor is expressed in embryonic mesenchymal and epithelial cells and its expression is reactivated in these adult cell types by proliferative signals or oxidative stress.
In vitro Reconstitution of an ABA Signaling Pathway
TLDR
This work shows that by combining the recently identified ABA receptor PYR1 with the type 2C protein phosphatase (PP2C) ABI1, the serine/threonine protein kinase SnRK2, and the transcription factor ABF2/AREB1, it can reconstitute ABA-triggered phosphorylation of the transcription factors in vitro and define a minimal set of core components of a complete major ABA signalling pathway.
Triple Loss of Function of Protein Phosphatases Type 2C Leads to Partial Constitutive Response to Endogenous Abscisic Acid1[C][W][OA]
TLDR
Results indicate that ABA response is finely tuned by the integrated action of these genes, which is required to prevent a constitutive response to endogenous ABA that might have a deleterious effect on growth and development in the absence of environmental stress.
HAB1–SWI3B Interaction Reveals a Link between Abscisic Acid Signaling and Putative SWI/SNF Chromatin-Remodeling Complexes in Arabidopsis[C][W]
TLDR
The results uncover SWI3B as a novel positive regulator of ABA signaling and suggest that HAB1 modulates ABA response through the regulation of a putative SWI/SNF chromatin-remodeling complex.
Modulation of Abscisic Acid Signaling in Vivo by an Engineered Receptor-Insensitive Protein Phosphatase Type 2C Allele1[C][W]
TLDR
expression of hab1W385A in Arabidopsis (Arabidopsis thaliana) plants leads to a strong, dominant ABA insensitivity, which demonstrates that this conserved tryptophan residue can be targeted for the generation of dominant clade A PP2C alleles.
The Coenzyme A Biosynthetic Enzyme Phosphopantetheine Adenylyltransferase Plays a Crucial Role in Plant Growth, Salt/Osmotic Stress Resistance, and Seed Lipid Storage1[W]
TLDR
Results suggest that the reaction catalyzed by PPAT is a regulatory step in the CoA biosynthetic pathway that plays a key role for plant growth, stress resistance, and seed lipid storage.
An Arabidopsis Mutant Impaired in Coenzyme A Biosynthesis Is Sugar Dependent for Seedling Establishment1
TLDR
Arabidopsis T-DNA knockout mutants of two CoA biosynthetic genes, HAL3A and HAL3B, are identified and characterized and point out the critical role of Coa biosynthesis during early postgerminative growth.
The Short-Rooted Phenotype of the brevis radix Mutant Partly Reflects Root Abscisic Acid Hypersensitivity1[C][W][OA]
TLDR
The results reveal an interaction between BRs, auxin, and ABA in the control of root growth and indicate that altered sensitivity to ABA is partly responsible for the brx short-root phenotype.
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