This study evaluated a modified, timed version of the "Get-Up and Go" Test (Mathias et al, 1986) in 60 patients referred to a Geriatric Day Hospital (mean age 79.5 years). The patient is observed and… (More)
Modified tests of association based on the correlation coefficient or the covariance between two spatially autocorrelated processes are presented. These tests can be used both for lattice and… (More)
There is evidence that type 2 diabetes mellitus is associated with cognitive impairment. Most studies investigating this association have evaluated elderly individuals, after many years of diabetes,… (More)
Covariate and confounder selection in case-control studies is often carried out using a statistical variable selection method, such as a two-step method or a stepwise method in logistic regression.… (More)
OBJECTIVE
To investigate the risk of adverse birth outcomes associated with residence near landfill sites in Great Britain.
DESIGN
Geographical study of risks of adverse birth outcomes in… (More)
OBJECTIVE
To evaluate the efficacy and safety of donepezil for severe Alzheimer disease (AD).
METHODS
Patients with severe AD (Mini-Mental State Examination [MMSE] scores 1 to 12 and Functional… (More)
We construct a unifying representation of the structure of measurement error problems with particular reference to situations commonly encountered in epidemiological studies, and outline how… (More)
OBJECTIVE
To investigate the risk of congenital anomalies in relation to an index of geographic density of landfill sites across 5x5 km grid squares in England.
METHODS
2 km zones were constructed… (More)
Germline CDH1 mutations confer a high lifetime risk of developing diffuse gastric (DGC) and lobular breast cancer (LBC). A multidisciplinary workshop was organised to discuss genetic testing,… (More)
This paper is concerned with the problem of estimating relative risks from ecological correlation studies. In the first part, some of the biases encountered when analysing aggregated data are… (More)