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Targeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapy
Extensive cancer research in the past few decades has identified the existence of a rare subpopulation of stem cells in the grove of cancer cells. These cells are known as the cancer stem cellsExpand
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Bacterial exopolysaccharide based nanoparticles for sustained drug delivery, cancer chemotherapy and bioimaging.
Introduction of a novel biocompatible, stable, biomaterial for drug delivery application remains always challenging. In the present study, we report the synthesis of an extremophilic bacterialExpand
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Smart Carriers and Nanohealers: A Nanomedical Insight on Natural Polymers
Biodegradable polymers are popularly being used in an increasing number of fields in the past few decades. The popularity and favorability of these materials are due to their remarkable properties,Expand
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Dual mode of cancer cell destruction for pancreatic cancer therapy using Hsp90 inhibitor loaded polymeric nano magnetic formulation.
Heat Shock Protein 90 (Hsp90) has been extensively explored as a potential drug target for cancer therapies. 17- N-allylamino- 17-demethoxygeldanamycin (17AAG) was the first Hsp90 inhibitor to enterExpand
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PEG Coated Biocompatible Cadmium Chalcogenide Quantum Dots for Targeted Imaging of Cancer Cells
Cancer stands as a leading cause of mortality worldwide and diagnostics of cancer still faces drawbacks. Optical imaging of cancer would allow early diagnosis, evaluation of disease progression andExpand
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Multifunctional Biocompatible Fluorescent Carboxymethyl Cellulose Nanoparticles
A multifunctional nanoparticle based on carboxymethyl cellulose was developed. Folate group was attached to nanoparticle for specific recognition of cancerous cells and 5FU was encapsulated forExpand
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Extremophilic polysaccharide for biosynthesis and passivation of gold nanoparticles and photothermal ablation of cancer cells
Extremophiles are the group of organisms that are far overlooked for exploring novel biomaterials in the field of material science and bionanotechnology. Extremophilic bacterial-sulfatedExpand
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Ecofriendly Route for the Synthesis of Highly Conductive Graphene Using Extremophiles for Green Electronics and Bioscience
Highly conductive biocompatible graphene is synthesized using ecofriendly reduction of graphene oxide (GO). Two strains of non-pathogenic extremophilic bacteria are used for reducing GO under bothExpand
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Green Approach for Augmenting Biocompatibility to Quantum Dots by Extremophilic Polysaccharide Conjugation and Nontoxic Bioimaging
The nanocrystals, so-called quantum dots (QDs), are undisputedly excellent fluorescent markers for imaging and clinical diagnostics. However, their toxicity is always a perturbing issue and remainsExpand
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Pharmaceutically versatile sulfated polysaccharide based bionano platforms.
UNLABELLED Sulfated polysaccharides are complex polysaccharide molecules with excellent physico-chemical properties and bioactivities. On the basis of origin, they are classified as plant, animal,Expand
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