Identification of acquired antimicrobial resistance genes
A web server providing a convenient way of identifying acquired antimicrobial resistance genes in completely sequenced isolates was created, and the method was evaluated on WGS chromosomes and plasmids of 30 isolates.
Multilocus Sequence Typing of Total-Genome-Sequenced Bacteria
A Web-based method for MLST of 66 bacterial species based on whole-genome sequencing data that enables investigators to determine the sequence types of their isolates on the basis of WGS data.
Population genomics of Bronze Age Eurasia
It is shown that the Bronze Age was a highly dynamic period involving large-scale population migrations and replacements, responsible for shaping major parts of present-day demographic structure in both Europe and Asia.
Richness of human gut microbiome correlates with metabolic markers
The authors' classifications based on variation in the gut microbiome identify subsets of individuals in the general white adult population who may be at increased risk of progressing to adiposity-associated co-morbidities.
An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia
It is shown that Aboriginal Australians are descendants of an early human dispersal into eastern Asia, possibly 62,000 to 75,000 years ago, which is separate from the one that gave rise to modern Asians 25, thousands of years ago.
Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans
The findings reveal that western Eurasian genetic signatures in modern-day Native Americans derive not only from post-Columbian admixture, as commonly thought, but also from a mixed ancestry of the First Americans.
Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
This work presents a method, based on binning co-abundant genes across a series of metagenomic samples, that enables comprehensive discovery of new microbial organisms, viruses and co-inherited genetic entities and aids assembly of microbial genomes without the need for reference sequences.
The genome of a Late Pleistocene human from a Clovis burial site in western Montana
The genome sequence of a male infant recovered from the Anzick burial site in western Montana is sequenced and it is shown that the gene flow from the Siberian Upper Palaeolithic Mal’ta population into Native American ancestors is also shared by the AnZick-1 individual and thus happened before 12,600 years bp.
Genomic evidence for the Pleistocene and recent population history of Native Americans
The results suggest that there has been gene flow between some Native Americans from both North and South America and groups related to East Asians and Australo-Melanesians, the latter possibly through an East Asian route that might have included ancestors of modern Aleutian Islanders.
Transcriptome Responses to Combinations of Stresses in Arabidopsis1[W][OA]
Plants have evolved to cope with combinations of stresses and, therefore, may be bred to endure them, and coexpression network modules responding to single and combined stresses are delineated.