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Screening for Celiac Disease in a North American Population: Sequential Serology and Gastrointestinal Symptoms
OBJECTIVES:The prevalence of diagnosed celiac disease is <1 in 2,000 in the United States, but screening studies undertaken in European and other populations have revealed a much higher prevalence.Expand
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Review article: coeliac disease, new approaches to therapy
Coeliac disease is managed by life‐long gluten withdrawal from the diet. However, strict adherence to a gluten‐free diet is difficult and is not always effective. Novel therapeutic approaches areExpand
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Distinct Role of Kruppel-like Factor 11 in the Regulation of Prostaglandin E2 Biosynthesis*
Kruppel-like factor (KLF) proteins are emerging as key regulators of lipid metabolism, diabetes, and the biosynthesis of immunological cytokines. However, their role in the synthesis ofExpand
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Crohn's Disease and Early Exposure to Domestic Refrigeration
Background Environmental risk factors playing a causative role in Crohn's Disease (CD) remain largely unknown. Recently, it has been suggested that refrigerated food could be involved in diseaseExpand
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Clinical and molecular features of young-onset colorectal cancer.
Colorectal cancer (CRC) is one of the leading causes of cancer related mortality worldwide. Although young-onset CRC raises the possibility of a hereditary component, hereditary CRC syndromes onlyExpand
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Combination testing for antibodies in the diagnosis of coeliac disease: comparison of multiplex immunoassay and ELISA methods
Background  Tissue transglutaminase (TTG) antibodies and newly developed deamidated gliadin peptide (DGP) antibodies have better accuracy than native gliadin antibodies. Multiplex immunoassay (MIA)Expand
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Epidemiologic characteristics of 500 patients with inflammatory bowel disease in Iran studied from 2004 through 2007.
BACKGROUND Despite claims of rarity, some studies indicate that the prevalence of inflammatory bowel disease has increased in Iran during the past decades. Establishment of a registry and theExpand
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Iron Deficiency in Long-Term Parenteral Nutrition Therapy.
BACKGROUND Iron is not routinely added to parenteral nutrition (PN) formulations in the United States because of the risk of anaphylaxis and concerns about incompatibilities. Studies have shown thatExpand
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Background: Osteoporosis has been frequently reported in patients with inflammatory bowel diseases, especially Crohn’s disease. Methods: All consecutive Crohn’s disease patients who attended the GIExpand
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Sessile Serrated Polyps and Colon Cancer Prevention
Evidence suggests that up to one fifth of colorectal carcinomas develop from serrated polyps, named for their pattern of colonic crypts, and include the sessile serrated adenoma/polyp (SSA/P) thatExpand
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