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Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation.
- B. Osterud, S. Rapaport
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences…
- 1 December 1977
A study was carried out on mechanisms, independent of activated Factor XI, capable of activating Factor IX. The reaction product of tissue factor and Factor VII functioned as a potent Factor IX… Expand
Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody.
Tissue factor, the cofactor for factor VIIa-catalyzed activation of factors IX and X, plays an important role in the initiation of hemostasis. However, the distribution of tissue factor in the body… Expand
The partial thromboplastin time with kaolin. A simple screening test for first stage plasma clotting factor deficiencies.
The partial thromboplastin time (PPT) test consists of recalcifying plasma in the presence of a lipid reagent that supplies optimal platelet thromboplastic factor-like activity. Thus, the test… Expand
Acquired inhibitors of blood coagulation.
Initiation and regulation of tissue factor-dependent blood coagulation.
Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway…
Rabbits were given polyclonal anti-tissue factor (TF) immunoglobulin G (IgG) before an injection of endotoxin to test the hypothesis that TF triggers disseminated intravascular coagulation (DIC)… Expand
Defibrination after brain-tissue destruction: A serious complication of head injury.
- S. Goodnight, G. Kenoyer, S. Rapaport, M. Patch, J. Lee, T. Kurze
- The New England journal of medicine
- 9 May 1974
Abstract A prospective study was conducted to evaluate defibrination after acute head trauma. Defibrination was not observed in 13 patients In whom trauma apparently did not destroy brain tissue. In… Expand
The extrinsic pathway inhibitor: a regulator of tissue factor-dependent blood coagulation.
- S. Rapaport
- Thrombosis and haemostasis
- 12 July 1991
The basalis of the primate endometrium: a bifunctional germinal compartment.
- H. A. Padykula, L. Coles, +5 authors I. R. Kaiserman-Abramof
- Biology, Medicine
- Biology of reproduction
- 1 March 1989
Radioautographic analysis of epithelial and stromal cell proliferation in the primate endometrial functionalis and basalis (rhesus monkey) has identified horizontal zonal patterns of mitotic… Expand
Correction of Excessive Anticoagulation with Low-Dose Oral Vitamin K1
Excessive anticoagulation with an international normalized ratio (INR) that exceeds 5.0 (a value > 5.0 increases the risk for hemorrhage) is common in patients who are receiving warfarin therapy… Expand