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Design, synthesis, and biological evaluation of dibromotyrosine analogues inspired by marine natural products as inhibitors of human prostate cancer proliferation, invasion, and migration.
- A. Sallam, S. Ramasahayam, S. Meyer, K. E. El Sayed
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 1 November 2010
Bioactive secondary metabolites originating from dibromotyrosine are common in marine sponges, such as sponges of the Aplysina species. Verongiaquinol (1),… Expand
Immunohistochemical expression of syndecan-1 in oral dysplastic epithelium.
- B. Lakkam, B. Majage, M. Astekar, R. S. Gugwad, G. Giri, S. Ramasahayam
- Journal of cancer research and therapeutics
BACKGROUND In stratified squamous epithelia, syndecan-1 is proposed to function as a cellto cell adhesion molecule, and plays an important role in regulation of cell growth and differentiation during… Expand
Chemometric regression techniques as emerging, powerful tools in genetic association studies
The field of chemometrics has its origin in chemistry and has been widely applied to the evaluation of analytical chemical data and quantitative structure-activity relationships. Chemometric… Expand
Effects of chemically characterized fractions from aerial parts of Echinacea purpurea and E. angustifolia on myelopoiesis in rats.
Echinacea species are used for beneficial effects on immune function, and various prevalent phytochemicals have immunomodulatory effects. Using a commercial E. purpurea (L.) Moench product, we have… Expand
Megakaryocyte expansion and macrophage infiltration in bone marrow of rats subchronically treated with MNX, N‐nitroso environmental degradation product of munitions compound RDX…
- S. Ramasahayam, Sridhar Jaligama, +4 authors S. Meyer
- Medicine, Chemistry
- Journal of applied toxicology : JAT
- 31 January 2017
Hexahydro‐1‐nitroso‐3,5‐dinitro‐1,3,5‐triazine (MNX), environmental degradation product of munitions hexahydro‐1,3,5‐trinitro‐1,3,5‐triazine (RDX), causes seizures in rats with acute oral exposure… Expand
Supercomputers in Modeling of Biological Systems
Modeling of biological systems has become an important facet in today’s scientific community because it has aided in the simulation of the minute biological entities comprising a living individual.… Expand