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hIAPP fibrillization implicated in Type 2 diabetes pathology involves formation of oligomers toxic to insulin producing pancreatic β-cells. We report design, synthesis, 3D structure and functional(More)
Amyloid is a highly insoluble, aggregated state of certain polypeptide sequences associated with a range of debilitating diseases. A key step in amyloid formation is the transition of a protein from(More)