S. Raemsby

Publications41
h-index11
Citations428
Highly Influential Citations5
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Potential neuroleptic agents. 3. Chemistry and antidopaminergic properties of substituted 6-methoxysalicylamides.
A series of substituted 6-methoxysalicylamides were synthesized from their corresponding 2,6-dimethoxybenzamides by demethylation of one methoxy group with boron tribromide. Substituted… Expand
  • 70
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Potential neuroleptic agents. 4. Chemistry, behavioral pharmacology, and inhibition of [3H]spiperone binding of 3,5-disubstituted N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-methoxysalicylamides.
A series of 3,5-disubstituted N-[(1-ethyl-2-pyrrolidinyl) methyl]-6-methoxysalicylamides was synthesized, starting from the 2,6-dimethoxybenzoic acids, by boron tribromide demethylation of the… Expand
  • 69
  • 2
New selective dopamine D-2 antagonists as antipsychotic agents. Pharmacological, chemical, structural and theoretical considerations.
  • 32
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Antidepressant agents. 1. Chemistry and pharmacology of amino-substituted spiro(5H-dibenzo(a,d)cycloheptene-5,1'-cycloalkanes).
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Potential Neuroleptic Agents. Part 4. Chemistry, Behavioral Pharmacology and Inhibition of [3H]Spiperone Binding of 3,5‐Disubstituted N‐[(1‐Ethyl‐2‐pyrrolidinyl)methyl]‐6‐methoxysalicylamides.
Die Carbonsauren (II) werden in die Amide (III) und (IV) umgewandelt, von denen (III) (R′, R2 = C1) auf Grund der Voruntersu-g chungsergebnisse klinisch gegen Schizophrenie untersucht werden soll.
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Synthesis of Npi- and Ntau-(2-Hydroxyethyl)-L-histidines.
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POTENTIAL NEUROLEPTIC AGENTS. 3. CHEMISTRY AND ANTIDOPAMINERGIC PROPERTIES OF F SUBSTITUTED 6-METHOXYSALICYLAMIDES
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Cyanide as an efficient and mild catalyst in the aminolysis of esters
  • 94
Crystallographic, theoretical and molecular modelling studies on the conformations of the salicylamide, raclopride, a selective dopamine‐D2 antagonist *
The structure of the potent dopamine‐D2 antagonist, raclopride, (S)‐3,5‐dichloro‐N‐[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐6‐methoxysalicylamide (+)‐tartrate, has been determined by X‐ray crystallography.… Expand
  • 17
Solid state conformations and antidopaminergic effects of remoxipride hydrochloride and a closely related salicylamide, FLA 797, in relation to dopamine receptor models.
The X-ray structures of two new 2,6-disubstituted benzamides, i.e., remoxipride hydrochloride monohydrate [-)-(S)-3-bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2,6-dimethoxybenza mide hydrochloride… Expand
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