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Nano spray dried antibacterial coatings for dental implants
Photodynamic Therapy of Ovarian Carcinoma Cells with Curcumin-Loaded Biodegradable Polymeric Nanoparticles
The novel nanoformulation facilitated the use of higher amounts of curcumin and showed strong apoptotic effects on tumour cells, and exhibited better physicochemical properties such as stability in the presence of light and improved serum stability compared to freeCurcumin.
A Novel Microparticulate Formulation with Allicin In Situ Synthesis
- B. Strehlow, U. Bakowsky, S. R. Pinnapireddy, J. Kusterer, G. Mielke, M. Keusgen
- 5 December 2016
For the first time in situ synthesised allicin was made available under safe and reproducible conditions for pulmonary application, which helps treating lung infections caused by a broad spectrum of pathogens at a low level of toxicity.
Preparation and Characterization of Curcumin Loaded Chitosan Nanoparticles for Photodynamic Therapy
Upon irradiation using a novel LED device, curcumin nanoparticles were able to generate ROS and destroy tumor cells and unloaded nanoparticles exhibited nonsignificant phototoxicity, confirming the importance of curcuming nanoparticles in enhancing the efficacy ofCurcumin and offering new insights in the field of PDT against cancer.
The application of STEP‐technology® for particle and protein dispersion detection studies in biopharmaceutical research
Glycosylated Artificial Virus-Like Hybrid Vectors for Advanced Gene Delivery
- S. R. Pinnapireddy, Mohamed Raafat El Assy, Patrick Schlote, U. Bakowsky
- Biology, EngineeringPolymers
- 1 February 2019
Improvement in the transfection efficiency was observed with the glycosylated HIV- and HSV-mimicking hybrid vectors, which also showed a safe biocompatible profile based on the cytotoxicity and haemocompatibility assays.
Lipid coated chitosan-DNA nanoparticles for enhanced gene delivery.
Curcumin loaded nanoparticles as efficient photoactive formulations against gram-positive and gram-negative bacteria.
Low level LED photodynamic therapy using curcumin loaded tetraether liposomes
Photodynamic therapy – hypericin tetraether liposome conjugates and their antitumor and antiangiogenic activity
It was demonstrated that the lipid composition and intraliposomal hypericin localization influenced the anti-vascular effect in the chorioallantoic membrane (CAM) and Hyp-HPβCD TEL liposomes could deliver the photosensitizer to the tumor site in a more protected manner.