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- Publications
- Influence
Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: Evidence for early up-regulation of the endosomal-lysosomal system
- A. Cataldo, J. L. Barnett, +5 authors R. Nixon
- Biology, Medicine
- Neuron
- 1 March 1995
In Alzheimer's disease brains, more than 90% of pyramidal neurons in lamina V and 70% in lamina III displayed 2- to 5-fold elevated levels of cathepsin D (Cat D) mRNA by in situ hybridization… Expand
Identification of an ionic strength sensitive nuclear protein kinase activity from the cervical carcinoma HeLa.
- S. Quarless
- Chemistry, Medicine
- Biochemical and biophysical research…
- 31 December 1985
A cyclic nucleotide independent, serine-threonine protein kinase activity has been purified approximately 700 fold from the nuclei of HeLa cells. This activity has a very strict ionic strength… Expand
Regulation of nerve growth factor gene expression in primary brain monolayer cultures: effects of dibutyryl cyclic AMP and sodium butyrate.
- S. Quarless, G. Heinrich
- Biology, Medicine
- Brain research
- 1 September 1987
Primary brain cultures composed of a heterogeneous population of cells, most of which reacted with anti-fibronectin and only few with anti-GFAP antiserum, were found to synthesize a mRNA… Expand
Analysis of RNA structure by ultraviolet crosslinking and denaturation gel electrophoresis.
- S. Quarless, C. Cantor
- Chemistry, Medicine
- Analytical biochemistry
- 1 June 1985
Electrophoresis in polyacrylamide gels containing both formamide and urea is a high-resolution technique for the analysis of crosslinked RNA species. Combined with a specific crosslinking agent like… Expand
Coupled endo-exodeoxyribonuclease activity from HeLa cell nuclei can function in an excision repair mode in vitro.
- S. Quarless
- Biology, Medicine
- Biochemical and biophysical research…
- 31 January 1985
A single strand specific coupled endo-exodeoxyribonuclease activity has been purified and characterized from the nuclei of HeLa cells(7). The novelity of this activity is in the nature of its… Expand
Identification of a deoxyribonuclease activity in the nuclei of the cervical carcinoma HeLa.
- S A Quarless
- Medicine
- Cancer biochemistry biophysics
- 1986
A deoxyribonuclease activity has been identified in the nuclei of the human cervical carcinoma HeLa. This activity has the novel property of existing as a single strand specific endo- and… Expand
Coupled endo-exodeoxyribonuclease activity from HeLa cell nuclei interacts with specific regions of the SV40 mini chromosome.
- S. Quarless
- Biology, Medicine
- Biochemical and biophysical research…
- 31 January 1985
A recently described endo-exodeoxyribonuclease activity (1) was determined to interact preferentially with the origin/enhancer region and the 5' end of the late promoter region of the SV40 mini… Expand