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Microsatellites in Malus X domestica (apple): abundance, polymorphism and cultivar identification

• Parry Guilford, S. Prakash, +4 authors Robert J Forster
• Theoretical and Applied Genetics
• 1997

Screening of an apple genomic library with (GA)15 and (GT)15 probes demonstrated that these repeats are abundant, occurring about every 120 and 190 kb, respectively. Microsatellites isolated from a… (More)

hRAD30 mutations in the variant form of xeroderma pigmentosum.

• R. E. Johnson, Christine M. Kondratick, S. Prakash, Louise Prakash
• Science
• 1999

Xeroderma pigmentosum (XP) is an autosomal recessive disease characterized by a high incidence of skin cancers. Yeast RAD30 encodes a DNA polymerase involved in the error-free bypass of ultraviolet… (More)

The Y-family of DNA polymerases.

• H. Ohmori, Errol C. Friedberg, +13 authors Rob G Woodgate
• Molecular cell
• 2001

ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal.

• C. Lee, Melissa Schwartz, S. Prakash, Masahiro Iwakura, Andreas Matouschek
• Molecular cell
• 2001

Protein unfolding is a key step in several cellular processes, including protein translocation across some membranes and protein degradation by ATP-dependent proteases. ClpAP protease and the… (More)

Nucleotide excision repair in yeast.

• S. Prakash, Louise Prakash
• Mutation research
• 2000

In nucleotide excision repair (NER) in eukaryotes, DNA is incised on both sides of the lesion, resulting in the removal of a fragment approximately 25-30 nucleotides long. This is followed by repair… (More)

Structure of the catalytic core of S. cerevisiae DNA polymerase eta: implications for translesion DNA synthesis.

• José Trincão, R. E. Johnson, Cipriano Escalante, S. Prakash, Louise Prakash, A. K. Aggarwal
• Molecular cell
• 2001

DNA polymerase eta is unique among eukaryotic polymerases in its proficient ability to replicate through a variety of distorting DNA lesions. We report here the crystal structure of the catalytic… (More)

Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities.

• Vanessa Bailly, Sarah N Lauder, S. Prakash, Louise Prakash
• The Journal of biological chemistry
• 1997

The RAD6 and RAD18 genes of Saccharomyces cerevisiae are required for postreplicative bypass of ultraviolet (UV)-damaged DNA and for UV mutagenesis. The RAD6 encoded protein is a ubiquitin… (More)

Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions.

• R. E. Johnson, M Todd Washington, Lajos Haracska, S. Prakash, Louise Prakash
• Nature
• 2000

DNA lesions can often block DNA replication, so cells possess specialized low-fidelity, and often error-prone, DNA polymerases that can bypass such lesions and promote replication of damaged DNA. The… (More)

Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stability.

• R. E. Johnson, Gopala K. Kovvali, Louise Prakash, S. Prakash
• The Journal of biological chemistry
• 1996

Defects in DNA mismatch repair result in instability of simple repetitive DNA sequences and elevated levels of spontaneous mutability. The human G/T mismatch binding protein, GTBP/p160, has been… (More)

Fidelity of human DNA polymerase eta.

• R. E. Johnson, M Todd Washington, S. Prakash, Louise Prakash
• The Journal of biological chemistry
• 2000

Xeroderma pigmentosum (XP) patients are highly sensitive to sunlight, and they suffer from a high incidence of skin cancers. The variant form of XP results from mutations in the hRAD30A gene, which… (More)

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