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Comparative behavioral effects of several anticholinergic agents in rats
The behavioral effects of JB 329 (Ditran) were compared with those of several anticholinergic agents in rats and the site of action of the tertiary compounds appears to be central. Expand
Effects of nicotine on self-stimulation in rats.
It is proposed that nicotine, by acting on a central nicotiniccholinergic receptor, may indirectly cause release of norepinephrine which, in turn, produces the facilitatory effect on sell-stimulation. Expand
Phencyclidine (PCP): Some human studies
- S. Pradhan
- Neuroscience & Biobehavioral Reviews
- 1 December 1984
The present review has summarized the observations of many investigators which showed that the acute effects of PCP following several routes of administration were shown to be dose-related and became irritable, argumentative or negative under the conditions of social stress and demanding tasks. Expand
Effects of nicotine on eeg and evoked potentials and their interactions with autonomic drugs
It is suggested that nicotine induces concomitant muscarinic and noradrenergic stimulations that are reflected in the time-course of action with initial cholinergic and subsequent noradRenergic preponderence. Expand
Comparative effects of nicotine and amphetamine on timing behavior in rats.
In case of both the drugs, a rough dose-effect relation could be demonstrated, and the inter-response time distributions were found to be shifted to the shorter class intervals, consistent increase occurring in the intermediate interval group. Expand
Carcinogenicity of some folk medicinal herbs in rats.
- G. Kapadia, E. Chung, +4 authors S. Pradhan
- Biology, Medicine
- Journal of the National Cancer Institute
- 1 March 1978
Twelve medicinal herbs were bioassayed to correlate a high incidence of esophageal carcinoma in natives of different places with their habitual consumption of these products. Outbred NIH Black rats… Expand
Pharmacology in Medicine Principles and Practice
Correlation of lithium effects on motor activity with its brain concentrations in rats
The time-course of the depressant effect of Li on motor activity correlated with the changes in Li concentrations in the brain areas related to emotion and psychomotor activity. Expand
Effects of toluene exposure on the spontaneous cortical activity in rats
- T. K. Ghosh, R. Copeland, J. C. Gear, S. Pradhan
- Medicine, Chemistry
- Pharmacology Biochemistry and Behavior
- 1 April 1989
Results indicate that the changes of EEG are a sensitive measure of the effects of toluene on the central nervous system (CNS) and its power spectra were measured. Expand
Effects of nicotine on several schedules of behavior in rats.
- S. Pradhan
- Archives internationales de pharmacodynamie et de…