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Hartnup disorder is caused by mutations in the gene encoding the neutral amino acid transporter SLC6A19
Hartnup disorder (OMIM 234500) is an autosomal recessive abnormality of renal and gastrointestinal neutral amino acid transport noted for its clinical variability. We localized a gene causing HartnupExpand
Preserved Central Memory and Activated Effector Memory CD4+ T-Cell Subsets in Human Immunodeficiency Virus Controllers: an ANRS EP36 Study
ABSTRACT Human immunodeficiency virus (HIV) controllers are rare individuals who spontaneously control HIV type 1 replication for 10 years or more in the absence of antiretroviral treatment. In theExpand
P‐glycoprotein: So Many Ways to Turn It On
Expression of the ABC transporter P‐glycoprotein (P‐gp or ABCB1) is associated with resistance to chemotherapy in cancer. However, early investigations into the regulation of ABCB1 expressionExpand
Rapid and Sensitive Detection of Severe Acute Respiratory Syndrome Coronavirus by Rolling Circle Amplification
ABSTRACT The severe acute respiratory syndrome (SARS) epidemic of 2003 was responsible for 774 deaths and caused significant economic damage worldwide. Since July 2003, a number of SARS cases haveExpand
Obstacles to successful antiretroviral treatment of HIV-1 infection: problems & perspectives.
Mutations in human immunodeficiency virus type 1 (HIV-1) are a major impediment to successful highly active antiretroviral therapy (HAART) and the design of anti-HIV vaccines. Although HAART has madeExpand
Assessment of drug resistance mutations in plasma and peripheral blood mononuclear cells at different plasma viral loads in patients receiving HAART.
BACKGROUND HIV drug resistance mutations both in peripheral blood mononuclear cells (PBMCs) and plasma have the ability to influence the outcome of highly active antiretroviral therapy for HIVExpand
HIV‐1 compartmentalization in diverse leukocyte populations during antiretroviral therapy
CD4+ T lymphocytes are the primary target of human immunodeficiency virus type 1 (HIV‐1), but there is increasing evidence that other immune cells in the blood, including CD8+ T lymphocytes andExpand
News and the British World
Webs, Networks, and Systems: Globalization and the Mass Media in the Nineteenth- and Twentieth-Century British Empire
  • S. Potter
  • History
  • Journal of British Studies
  • 1 July 2007
W have of late been encouraged to think of Britain’s imperial past in terms of “webs” and “networks.” Scholars of contemporary globalization, seeking precedent for current perceived trends, have usedExpand