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A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis
BACKGROUND Neuromyelitis optica is an inflammatory demyelinating disease with generally poor prognosis that selectively targets optic nerves and spinal cord. It is commonly misdiagnosed as multiple… Expand
The spectrum of neuromyelitis optica
- D. Wingerchuk, V. Lennon, C. Lucchinetti, S. Pittock, B. Weinshenker
- The Lancet Neurology
- 1 September 2007
Neuromyelitis optica (also known as Devic's disease) is an idiopathic, severe, demyelinating disease of the central nervous system that preferentially affects the optic nerve and spinal cord.… Expand
IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel
- V. Lennon, T. Kryzer, S. Pittock, A. Verkman, S. Hinson
- Biology, Medicine
- The Journal of experimental medicine
- 15 August 2005
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that selectively affects optic nerves and spinal cord. It is considered a severe variant of multiple sclerosis (MS), and frequently… Expand
Revised diagnostic criteria for neuromyelitis optica
Background: The authors previously proposed diagnostic criteria for neuromyelitis optica (NMO) that facilitate its distinction from prototypic multiple sclerosis (MS). However, some patients with… Expand
Revised diagnostic criteria for neuromyelitis optica.
BACKGROUND The authors previously proposed diagnostic criteria for neuromyelitis optica (NMO) that facilitate its distinction from prototypic multiple sclerosis (MS). However, some patients with… Expand
Brain abnormalities in neuromyelitis optica.
- S. Pittock, V. Lennon, K. Krecke, D. Wingerchuk, C. Lucchinetti, B. Weinshenker
- Archives of neurology
- 1 March 2006
BACKGROUND Neuromyelitis optica (NMO) is a severe demyelinating disease defined principally by its tendency to selectively affect optic nerves and the spinal cord causing recurrent attacks of… Expand
Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis
- C. Lucchinetti, R. Gavrilova, +13 authors W. Brueck
- Brain : a journal of neurology
- 4 June 2008
Atypical imaging features of multiple sclerosis lesions include size >2 cm, mass effect, oedema and/or ring enhancement. This constellation is often referred to as ‘tumefactive multiple sclerosis’.… Expand
Steroid-responsive encephalopathy associated with autoimmune thyroiditis.
BACKGROUND Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), often termed Hashimoto encephalopathy, is a poorly understood and often misdiagnosed entity. OBJECTIVE… Expand
Neuromyelitis optica and non organ-specific autoimmunity.
BACKGROUND Neuromyelitis optica (NMO) is often associated with other clinical or serological markers of non-organ-specific autoimmunity. OBJECTIVE To evaluate the relationship between NMO spectrum… Expand
Neuromyelitis optica brain lesions localized at sites of high aquaporin 4 expression.
- S. Pittock, B. Weinshenker, C. Lucchinetti, D. Wingerchuk, J. Corboy, V. Lennon
- Archives of neurology
- 1 July 2006
BACKGROUND Neuromyelitis optica (NMO)-IgG is a specific autoantibody marker for NMO. It binds selectively to aquaporin 4 (AQP4), which is highly concentrated in astrocytic foot processes at the… Expand