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The heterochromatin protein 1 prevents telomere fusions in Drosophila.
HP1 (Heterochromatin protein 1) is a conserved, non-histone chromosomal protein that is best known for its preferential binding to pericentric heterochromatin and its role in position effectExpand
The ISWI chromatin-remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo.
Drosophila ISWI, a highly conserved member of the SWI2/SNF2 family of ATPases, is the catalytic subunit of three chromatin-remodeling complexes: NURF, CHRAC, and ACF. To clarify the biologicalExpand
HP1 controls telomere capping, telomere elongation, and telomere silencing by two different mechanisms in Drosophila.
HP1 is a conserved chromosomal protein, first discovered in Drosophila, which is predominantly associated with the heterochromatin of many organisms. Recently, it has been shown that HP1 is requiredExpand
Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals
Abstract. We show that methylated lysine 9 of histone H3 (Me9H3) is a marker of heterochromatin in divergent animal species. It localises to both constitutive and facultative heterochromatin andExpand
Heterochromatin and tri-methylated lysine 20 of histone H4 in animals
Tri-methylated lysine 20 on histone H4 (Me(3)K20H4) is a marker of constitutive heterochromatin in murine interphase and metaphase cells. Heterochromatin marked by Me(3)K20H4 replicates late during SExpand
Functional elements in Drosophila melanogaster heterochromatin.
INTRODUCTION 239 THE STRUCTURE OF DROSOPHILA MELANOGASTER HETEROCHROMATIN . 241 THE HETEROCHROMATIC FUNCTIONAL ELEMENTS . . . . . . . . . . . . . . . . 246 The Y-Chromosome Fertility Factors . . ...Expand
Heterochromatin Protein 1 (HP1a) Positively Regulates Euchromatic Gene Expression through RNA Transcript Association and Interaction with hnRNPs in Drosophila
Heterochromatin Protein 1 (HP1a) is a well-known conserved protein involved in heterochromatin formation and gene silencing in different species including humans. A general model has been proposedExpand
Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons
The canalization concept describes the resistance of a developmental process to phenotypic variation, regardless of genetic and environmental perturbations, owing to the existence of bufferingExpand
Transposable elements are stable structural components of Drosophila melanogaster heterochromatin.
We determined the distribution of 11 different transposable elements on Drosophila melanogaster mitotic chromosomes by using high-resolution fluorescent in situ hybridization (FISH) coupled withExpand
Heterochromatin protein 1 (HP1) is associated with induced gene expression in Drosophila euchromatin
Heterochromatin protein 1 (HP1) is a conserved nonhistone chromosomal protein, which is involved in heterochromatin formation and gene silencing in many organisms. In addition, it has been shown thatExpand
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