Alkaloid Spectrum in Diploid and Tetraploid Hairy Root Cultures of Datura stramonium
- S. Berkov, A. Pavlov, P. Kovatcheva, P. Stanimirova, S. Philipov
- Biology, MedicineZeitschrift für Naturforschung C - A Journal of…
- 1 February 2003
Hairy root cultures were obtained from diploid and induced tetraploid plants of Datura stramonium and analyzed by gas chromatography/mass spectrometry and a new tropane ester 3-tigloyloxy-6-propionyloxy-7-hydroxytropane was identified on the basis of mass spectral data.
Study on the anti-inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids.
- N. Ivanovska, S. Philipov
- MedicineInternational Journal of Immunopharmacology
- 1 October 1996
Comparative study of the alkaloids in tribe Datureae and their chemosystematic significance
- T. Doncheva, S. Berkov, S. Philipov
- 1 June 2006
GC-MS Investigation of Tropane Alkaloids in Datura stramonium
- S. Philipov, S. Berkov
- ChemistryZeitschrift für Naturforschung C - A Journal of…
- 1 June 2002
The alkaloid spectrumin roots, leaves and seeds of Datura stramonium L. was investigated by GC-MS. Twenty-nine tropane alkaloids are detected. Twelve of themare new constituents for the species and…
Ontogenetic variation of the tropane alkaloids in Datura stramonium
- S. Berkov, T. Doncheva, S. Philipov, K. Alexandrov
- 1 October 2005
Alkaloid Production in Diploid and Autotetraploid Plants of Datura stramonium
- S. Berkov, S. Philipov
- 1 January 2002
Two 3-tigloyloxy-6-isovaleryloxy-7- hydroxytropane isomers were detected for the first time in genus Datura and scopolamine was the main alkaloid in the leaves of both ploid forms.
Antimicrobial and immunological activity of ethanol extracts and fractions from Isopyrum thalictroides.
- N. Ivanovska, S. Philipov, R. Istatkova, P. Georgieva
- Medicine, ChemistryJournal of Ethnopharmacology
- 1 November 1996
Phosphatidylinositol 4‐kinase III beta is the target of oxoglaucine and pachypodol (Ro 09‐0179) for their anti‐poliovirus activities, and is located at upstream of the target step of brefeldin A
- M. Arita, S. Philipov, A. Galabov
- Biology, ChemistryMicrobiology and immunology
- 1 June 2015
The results suggest that PI4KB is a major target of anti‐picornavirus compounds identified in vitro for their anti-picORNavirus activities and for some uncharacterized biological phenomena caused by these compounds, and that BFA and PI4 KB/OSBP inhibitors synergistically repress PV replication by targeting distinct steps in viral RNA replication.