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Risk of congenital heart disease in relatives of probands with conotruncal cardiac defects: An evaluation of 1,620 families
Current recurrence risk counseling for conotruncal cardiac defects (CTD) is based on empiric estimates from multiple studies. We examined the risk of congenital heart disease (CHD) in relatives ofExpand
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22q11.2 Deletions in Patients with Conotruncal Defects: Data from 1,610 Consecutive Cases
The 22q11.2 deletion syndrome is characterized by multiple congenital anomalies including conotruncal cardiac defects. Identifying the patient with a 22q11.2 deletion (22q11del) can be challengingExpand
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The association between cardiac physiology, acquired brain injury, and postnatal brain growth in critical congenital heart disease
Objective To assess the trajectory of perioperative brain growth in relationship to cardiac diagnosis and acquired brain injuries. Methods This was a cohort study of term neonates with hypoplasticExpand
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Neonatal Brain Injury and Timing of Neurodevelopmental Assessment in Patients With Congenital Heart Disease.
BACKGROUND Brain injury (BI) is reported in 60% of newborns with critical congenital heart disease as white matter injury (WMI) or stroke. Neurodevelopmental (ND) impairments are reported in theseExpand
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The many faces of hydrops.
PURPOSE Fetal hydrops arises from multiple disease processes and can portend a grim prognosis. We reviewed our experience with hydropic fetuses to understand relevant antenatal anatomic andExpand
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White matter injury in term neonates with congenital heart diseases: Topology & comparison with preterm newborns
We quantitatively assess the volume and location of WMI in term CHD neonates and compare them with preterm neonates. Expand
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Timing and Mode of Delivery in Prenatally Diagnosed Congenital Heart Disease- an Analysis of Practices within the University of California Fetal Consortium (UCfC)
Prenatal diagnosis of critical congenital heart disease (CHD) is associated with decreased morbidity. It is also associated with lower birth weights and earlier gestational age at delivery. TheExpand
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Right Ventricular Systolic-to-Diastolic Time Index: Hypoplastic Left Heart Fetuses Differ Significantly from Normal Fetuses.
BACKGROUND A growing body of evidence indicates that right ventricular dysfunction in patients with palliated hypoplastic left heart syndrome (HLHS) originates in fetal life. In this study, theExpand
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Coarctation Index Predicts Recurrent Aortic Arch Obstruction Following Surgical Repair of Coarctation of the Aorta in Infants
Recurrent aortic arch obstruction (RAAO) remains a major cause of morbidity following surgical neonatal repair of coarctation of the aorta (CoA). Elucidating predictors of RAAO can identify high-riskExpand
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Association of Prenatal Diagnosis of Critical Congenital Heart Disease With Postnatal Brain Development and the Risk of Brain Injury.
IMPORTANCE The relationship of prenatal diagnosis of critical congenital heart disease (CHD) with brain injury and brain development is unknown. Given limited improvement of CHD outcomes withExpand
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