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Electrostatic Self-Assembled Chitosan-Pectin Nano- and Microparticles for Insulin Delivery
TLDR
In vitro tests indicated that the proposed system presents potential as a drug delivery for oral administration of bioactive peptides without chemical crosslinkers based on natural and biodegradable polysaccharides. Expand
Synergistic effect of quercetin and pH-responsive DEAE-chitosan carriers as drug delivery system for breast cancer treatment.
TLDR
In vitro studies indicated that the DEAE-modified chitosan nanoaggregates showed a synergistic effect with quercetin on the control of the viability of MCF-7 cells, therefore, DEae- modified chito-N,N-diethylethylamine hydrochloride with pH-sensibility can be used as optimized nanocarriers in cancer therapy. Expand
A Chitosan—Based Liposome Formulation Enhances the In Vitro Wound Healing Efficacy of Substance P Neuropeptide
TLDR
The amenability of chitosan-based nanomaterials to encapsulate peptides and proteins constitutes a promising approach towards potential novel therapies to treat difficult wounds. Expand
Antiquorum sensing, antibiofilm formation and cytotoxicity activity of commonly used medicinal plants by inhabitants of Borabu sub-county, Nyamira County, Kenya
TLDR
Cytotoxicity assays with mammalian MDCK cells also did indicate that the selected extracts with putative AQS activity, also reduced the cell viability, therefore, further studies will be needed to separate and re-test the individual compounds especially from the selected two promising plants. Expand
Self‐assembled amphiphilic chitosan nanoparticles for quercetin delivery to breast cancer cells
TLDR
Results suggest that nanoparticles might be a promising pH‐sensitive drug delivery system for applications in anticancer treatment and Haemocompatibility test results suggest that the nanoparticles exhibit suitable blood compatibility for biological applications. Expand
Self‐aggregated nanoparticles of N‐dodecyl,N′‐glycidyl(chitosan) as pH‐responsive drug delivery systems for quercetin
In this study, pH-responsive amphiphilic chitosan (CS) nanoparticles were used to encapsulate quercetin (QCT) for sustained release in cancer therapy. The novel CS derivatives were obtained byExpand
New approaches for the analysis of confluent cell layers with quantitative phase digital holographic microscopy
Digital holographic microscopy (DHM) enables high resolution non-destructive inspection of technical surfaces and minimally-invasive label-free live cell imaging. However, the analysis of confluentExpand
Chitosan-based nanomaterials for drug delivery and antibiotic-free bacterial control
Research focused on chitosan (CS)-based nanostructured materials have become well-contrasted effective drug and gene delivery platforms, particularly for transmucosal administration. The biologicalExpand